The heterogeneity of arylhydrocarbon hydroxylase in fetal liver microsomes of rats

Keinosuke Mizokami, Momoko Sunouchi, Kazuhide Inoue, Kannosuke Fujimori, Akira Takanaka, Yoshihito Omori, Toshitsugu Yubisui

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The characteristic of arylhydrocarbon hydroxylase system in fetal liver microsomes of rat was investigated. NADH-synergistic effect on NADPH-dependent arylhydrocarbon hydroxylase was observed in fetal liver microsomes of rat but not in maternal liver microsomes. NADH-synergistic effect decreased in parallel with the decrease of the ratio of cytochrome b5/cytochrome P-450 in liver microsomes. The cytochrome P-450 in arylhydrocarbon hydroxylase system in fetal liver microsomes of rat seemed to be different from that in offspring liver microsomes in respect of its dependency on cytochrome b5 system for its maximum activity.

Original languageEnglish
Pages (from-to)59-64
Number of pages6
JournalBiochemical and Biophysical Research Communications
Volume113
Issue number1
DOIs
Publication statusPublished - May 31 1983
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology

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