The Hypothalamic-Pituitary-Adrenal Axis and Gut Microbiota: A Target for Dietary Intervention?

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Citations (Scopus)

Abstract

Gut microbiota not only play a principal role in the postnatal maturation of the mammalian immune system, but they also are responsible for a vast array of metabolic activities, including food digestion and production of biologically active substances. Moreover, it is rapidly becoming apparent that gut microbes can also affect the development and regulation of the hypothalamic-pituitary-adrenal (HPA) axis and regulate other behaviors. Herein we focus on the signaling pathway from gut microbiota to the brain in terms of commensal microbiota affecting the HPA axis response, and we further emphasize the therapeutic potential of dietary factors, such as probiotics and short-chain fatty acids, for people with stress-related diseases.

Original languageEnglish
Title of host publicationThe Gut-Brain Axis Dietary, Probiotic, and Prebiotic Interventions on the Microbiota
PublisherElsevier Inc.
Pages293-304
Number of pages12
ISBN (Electronic)9780128025444
ISBN (Print)9780128023044
DOIs
Publication statusPublished - Jun 2 2016

Fingerprint

Volatile Fatty Acids
Microbiota
Probiotics
Digestion
Immune System
Food
Brain
Gastrointestinal Microbiome
Therapeutics

All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)

Cite this

Sudo, N. (2016). The Hypothalamic-Pituitary-Adrenal Axis and Gut Microbiota: A Target for Dietary Intervention? In The Gut-Brain Axis Dietary, Probiotic, and Prebiotic Interventions on the Microbiota (pp. 293-304). Elsevier Inc.. https://doi.org/10.1016/B978-0-12-802304-4.00013-X

The Hypothalamic-Pituitary-Adrenal Axis and Gut Microbiota : A Target for Dietary Intervention? / Sudo, Nobuyuki.

The Gut-Brain Axis Dietary, Probiotic, and Prebiotic Interventions on the Microbiota. Elsevier Inc., 2016. p. 293-304.

Research output: Chapter in Book/Report/Conference proceedingChapter

Sudo, N 2016, The Hypothalamic-Pituitary-Adrenal Axis and Gut Microbiota: A Target for Dietary Intervention? in The Gut-Brain Axis Dietary, Probiotic, and Prebiotic Interventions on the Microbiota. Elsevier Inc., pp. 293-304. https://doi.org/10.1016/B978-0-12-802304-4.00013-X
Sudo N. The Hypothalamic-Pituitary-Adrenal Axis and Gut Microbiota: A Target for Dietary Intervention? In The Gut-Brain Axis Dietary, Probiotic, and Prebiotic Interventions on the Microbiota. Elsevier Inc. 2016. p. 293-304 https://doi.org/10.1016/B978-0-12-802304-4.00013-X
Sudo, Nobuyuki. / The Hypothalamic-Pituitary-Adrenal Axis and Gut Microbiota : A Target for Dietary Intervention?. The Gut-Brain Axis Dietary, Probiotic, and Prebiotic Interventions on the Microbiota. Elsevier Inc., 2016. pp. 293-304
@inbook{735ac622b3a3425ba4c56084924386d7,
title = "The Hypothalamic-Pituitary-Adrenal Axis and Gut Microbiota: A Target for Dietary Intervention?",
abstract = "Gut microbiota not only play a principal role in the postnatal maturation of the mammalian immune system, but they also are responsible for a vast array of metabolic activities, including food digestion and production of biologically active substances. Moreover, it is rapidly becoming apparent that gut microbes can also affect the development and regulation of the hypothalamic-pituitary-adrenal (HPA) axis and regulate other behaviors. Herein we focus on the signaling pathway from gut microbiota to the brain in terms of commensal microbiota affecting the HPA axis response, and we further emphasize the therapeutic potential of dietary factors, such as probiotics and short-chain fatty acids, for people with stress-related diseases.",
author = "Nobuyuki Sudo",
year = "2016",
month = "6",
day = "2",
doi = "10.1016/B978-0-12-802304-4.00013-X",
language = "English",
isbn = "9780128023044",
pages = "293--304",
booktitle = "The Gut-Brain Axis Dietary, Probiotic, and Prebiotic Interventions on the Microbiota",
publisher = "Elsevier Inc.",
address = "United States",

}

TY - CHAP

T1 - The Hypothalamic-Pituitary-Adrenal Axis and Gut Microbiota

T2 - A Target for Dietary Intervention?

AU - Sudo, Nobuyuki

PY - 2016/6/2

Y1 - 2016/6/2

N2 - Gut microbiota not only play a principal role in the postnatal maturation of the mammalian immune system, but they also are responsible for a vast array of metabolic activities, including food digestion and production of biologically active substances. Moreover, it is rapidly becoming apparent that gut microbes can also affect the development and regulation of the hypothalamic-pituitary-adrenal (HPA) axis and regulate other behaviors. Herein we focus on the signaling pathway from gut microbiota to the brain in terms of commensal microbiota affecting the HPA axis response, and we further emphasize the therapeutic potential of dietary factors, such as probiotics and short-chain fatty acids, for people with stress-related diseases.

AB - Gut microbiota not only play a principal role in the postnatal maturation of the mammalian immune system, but they also are responsible for a vast array of metabolic activities, including food digestion and production of biologically active substances. Moreover, it is rapidly becoming apparent that gut microbes can also affect the development and regulation of the hypothalamic-pituitary-adrenal (HPA) axis and regulate other behaviors. Herein we focus on the signaling pathway from gut microbiota to the brain in terms of commensal microbiota affecting the HPA axis response, and we further emphasize the therapeutic potential of dietary factors, such as probiotics and short-chain fatty acids, for people with stress-related diseases.

UR - http://www.scopus.com/inward/record.url?scp=85011739946&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85011739946&partnerID=8YFLogxK

U2 - 10.1016/B978-0-12-802304-4.00013-X

DO - 10.1016/B978-0-12-802304-4.00013-X

M3 - Chapter

AN - SCOPUS:85011739946

SN - 9780128023044

SP - 293

EP - 304

BT - The Gut-Brain Axis Dietary, Probiotic, and Prebiotic Interventions on the Microbiota

PB - Elsevier Inc.

ER -