The hypothalamo-sympathetic nervous system modulates peripheral cellular immunity

T. Hori, T. Katafuchi, Sachiko Take, Y. Kaizuka, T. Ichijo, N. Shimizu

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)

Abstract

Our findings reviewed in this article have revealed that the stimulation of opioid receptors of the hypothalamic neurons by interferon α or β-endorphin synthesized in the brain or by stress causing the opioid-dependent analgesia suppresses the natural killer cytotoxicity, an important component of immunosurveillance, through an activation of the hypothalamic CRF-sympathetic nervous system.

Original languageEnglish
Pages (from-to)309-317
Number of pages9
JournalNeurobiology
Volume3
Issue number3-4
Publication statusPublished - 1995

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)

Fingerprint

Dive into the research topics of 'The hypothalamo-sympathetic nervous system modulates peripheral cellular immunity'. Together they form a unique fingerprint.

Cite this