The IASLC/ITMIG thymic epithelial tumors staging project: Proposal for an evidence-based stage classification system for the forthcoming (8th) edition of the TNM classification of malignant tumors

Frank C. Detterbeck, Kelly Stratton, Dorothy Giroux, Hisao Asamura, John Crowley, Conrad Falkson, Pier Luigi Filosso, Aletta A. Frazier, Giuseppe Giaccone, James Huang, Jhingook Kim, Kazuya Kondo, Marco Lucchi, Mirella Marino, Edith M. Marom, Andrew G. Nicholson, Meinoshin Okumura, Enrico Ruffini, Paul Van Schil, Peter GoldstrawRamón Rami-Porta, David Ball, David Beer, Ricardo Beyruti, Vanessa Bolejack, Kari Chansky, Wilfried Ernst Erich Eberhardt, John Edwards, Françoise Galateau-Sallé, Fergus Gleeson, Patti Groome, Catherine Kennedy, Laura Kingsbury, Young Tae Kim, Haruhiko Kondo, Mark Krasnik, Kaoru Kubota, Antoon Lerut, Gustavo Lyons, Jan Van Meerbeeck, Alan Mitchell, Takashi Nakano, Anna Nowak, Michael Peake, Thomas Rice, Kenneth Rosenzweig, Valerie Rusch, Nagahiro Saijo, Jean Paul Sculier, Lynn Shemanski

Research output: Contribution to journalArticle

141 Citations (Scopus)


A universal and consistent stage classification system, which describes the anatomic extent of a cancer, provides a foundation for communication and collaboration. Thymic epithelial malignancies have seen little progress, in part because of the lack of an official system. The International Association for the Study of Lung Cancer and the International Thymic Malignancies Interest Group assembled a large retrospective database, a multispecialty international committee and carried out extensive analysis to develop proposals for the 8th edition of the stage classification manuals. This tumor, node, metastasis (TNM)-based system is applicable to all types of thymic epithelial malignancies. This article summarizes the proposed definitions of the T, N, and M components and describes how these are combined into stage groups. This represents a major step forward for thymic malignancies.

Original languageEnglish
Pages (from-to)S65-S72
JournalJournal of Thoracic Oncology
Issue number9
Publication statusPublished - Jan 1 2014


All Science Journal Classification (ASJC) codes

  • Oncology
  • Pulmonary and Respiratory Medicine

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