The IASLC/ITMIG thymic epithelial tumors staging project: Proposals for the N and M components for the forthcoming (8th) edition of the TNM classification of malignant tumors

Kazuya Kondo, Paul Van Schil, Frank C. Detterbeck, Meinoshin Okumura, Dorothy Giroux, Hisao Asamura, John Crowley, Conrad Falkson, Pier Luigi Filosso, Giuseppe Giaccone, James Huang, Jhingook Kim, Marco Lucchi, Mirella Marino, Edith M. Marom, Andrew G. Nicholson, Enrico Ruffini, Peter Goldstraw, Ramón Rami-Porta, David BallDavid Beer, Ricardo Beyruti, Vanessa Bolejack, Kari Chansky, Wilfried Ernst Erich Eberhardt, John Edwards, Françoise Galateau-Sallé, Fergus Gleeson, Patti Groome, Catherine Kennedy, Laura Kingsbury, Young Tae Kim, Haruhiko Kondo, Mark Krasnik, Kaoru Kubota, Antoon Lerut, Gustavo Lyons, Jan Van Meerbeeck, Alan Mitchell, Takashi Nakano, Anna Nowak, Michael Peake, Thomas Rice, Kenneth Rosenzweig, Valerie Rusch, Nagahiro Saijo, Jean Paul Sculier, Lynn Shemanski, Kelly Stratton, Kenji Suzuki

Research output: Contribution to journalArticlepeer-review

66 Citations (Scopus)

Abstract

Stage classification is an important underpinning of management of patients with cancer, and rests on a combination of three components: T for tumor extent, N for nodal involvement, and M for more distant metastases. This article details an initiative to develop proposals for the first official stage classification system for thymic malignancies for the 8th edition of the stage classification manuals. Specifically, the results of analysis of a large database and the considerations leading to the proposed N and M components are described. Nodal involvement is divided into an anterior (N1) and a deep (N2) category. Metastases can involve pleural or pericardial nodules (M1a) or intraparenchymal pulmonary nodules or metastases to distant sites (M1b).

Original languageEnglish
Pages (from-to)S81-S87
JournalJournal of Thoracic Oncology
Volume9
Issue number9
DOIs
Publication statusPublished - Jan 1 2014

All Science Journal Classification (ASJC) codes

  • Oncology
  • Pulmonary and Respiratory Medicine

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