The impact of rTMS over the dorsolateral prefrontal cortex on cognitive processing

A. Sato, T. Torii, Y. Nakahara, M. Iwahashi, Y. Itoh, Keiji Iramina

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Citations (Scopus)

Abstract

The purpose of the present study was to use event-related potentials (ERP) to clarify the effect of magnetic stimulation on cognitive processing. A figure eight-shaped flat repetitive transcranial magnetic stimulation (rTMS) coil was used to stimulate either the region over the left or the right dorsolateral prefrontal cortex, which is considered to be the origin of the P300 component. Stimulus frequencies were 1.00, 0.75 and 0.50 Hz rTMS. The strength of the magnetic stimulation was set at 80% of the motor threshold for each participant. The auditory oddball task was used to elicit P300s before and shortly after rTMS, and comprised a sequence of sounds containing standard (1 kHz pure tone, 80% of trials) and deviant (2 kHz pure tone, 20% of trials) stimuli. We found that a 1.00 Hz rTMS pulse train over the left dorsolateral prefrontal cortex increased P300 latencies by 8.50 ms at Fz, 12.85 ms at Cz, and 11.25 ms at Pz. In contrast, neither 0.75 and 0.50 Hz rTMS pulse trains over the left dorsolateral prefrontal cortex nor 1.00, 0.75 and 0.50 Hz rTMS pulse trains over the right dorsolateral prefrontal cortex altered P300 latencies. These results indicate that rTMS frequency affects cognitive processing. Thus, we suggest that the effects of rTMS vary according to the activity of excitatory and inhibitory neurons in the cerebral cortex.

Original languageEnglish
Title of host publication2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013
Pages1988-1991
Number of pages4
DOIs
Publication statusPublished - Oct 31 2013
Event2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013 - Osaka, Japan
Duration: Jul 3 2013Jul 7 2013

Other

Other2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013
CountryJapan
CityOsaka
Period7/3/137/7/13

Fingerprint

Transcranial Magnetic Stimulation
Prefrontal Cortex
Processing
Neurons
Acoustic waves
P300 Event-Related Potentials
Evoked Potentials
Cerebral Cortex

All Science Journal Classification (ASJC) codes

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

Cite this

Sato, A., Torii, T., Nakahara, Y., Iwahashi, M., Itoh, Y., & Iramina, K. (2013). The impact of rTMS over the dorsolateral prefrontal cortex on cognitive processing. In 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013 (pp. 1988-1991). [6609919] https://doi.org/10.1109/EMBC.2013.6609919

The impact of rTMS over the dorsolateral prefrontal cortex on cognitive processing. / Sato, A.; Torii, T.; Nakahara, Y.; Iwahashi, M.; Itoh, Y.; Iramina, Keiji.

2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013. 2013. p. 1988-1991 6609919.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Sato, A, Torii, T, Nakahara, Y, Iwahashi, M, Itoh, Y & Iramina, K 2013, The impact of rTMS over the dorsolateral prefrontal cortex on cognitive processing. in 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013., 6609919, pp. 1988-1991, 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013, Osaka, Japan, 7/3/13. https://doi.org/10.1109/EMBC.2013.6609919
Sato A, Torii T, Nakahara Y, Iwahashi M, Itoh Y, Iramina K. The impact of rTMS over the dorsolateral prefrontal cortex on cognitive processing. In 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013. 2013. p. 1988-1991. 6609919 https://doi.org/10.1109/EMBC.2013.6609919
Sato, A. ; Torii, T. ; Nakahara, Y. ; Iwahashi, M. ; Itoh, Y. ; Iramina, Keiji. / The impact of rTMS over the dorsolateral prefrontal cortex on cognitive processing. 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013. 2013. pp. 1988-1991
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