Abstract
Mushrooms contain large quantities of α-glucans. Shiitake (Lentinula edodes), Japan's most popular edible mushroom, has been reported to contain about 6% (weight/dried weight) of α-(1,3)-glucan. This glucan is one of the major components of oral biofilm formed by the cariogenic bacteria Streptococcus mutans and Streptococcus sobrinus. We found that extracts from shiitake and other edible mushrooms could reduce preformed biofilms of S. mutans and S. sobrinus in the presence of dextranase. We also investigated the α-glucanase activities of shiitake mushroom extracts and their effects on biofilm formation. The extracts possessed α-glucanase activity and degraded water-insoluble glucans from mutans streptococci. The extracts strongly inhibited the sucrose-dependent formation of biofilms by S. mutans and S. sobrinus in the presence of dextranase. Our results suggest that some components of mushrooms, including α-glucanases, might inhibit the sucrose-induced formation of oral biofilms.
| Original language | English |
|---|---|
| Pages (from-to) | 615-623 |
| Number of pages | 9 |
| Journal | Applied Microbiology and Biotechnology |
| Volume | 86 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Mar 1 2010 |
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All Science Journal Classification (ASJC) codes
- Biotechnology
- Applied Microbiology and Biotechnology
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The inhibitory effects of mushroom extracts on sucrose-dependent oral biofilm formation. / Yano, Akira; Kikuchi, Sayaka; Yamashita, Yoshihisa; Sakamoto, Yuichi; Nakagawa, Yuko; Yoshida, Yasuo.
In: Applied Microbiology and Biotechnology, Vol. 86, No. 2, 01.03.2010, p. 615-623.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The inhibitory effects of mushroom extracts on sucrose-dependent oral biofilm formation
AU - Yano, Akira
AU - Kikuchi, Sayaka
AU - Yamashita, Yoshihisa
AU - Sakamoto, Yuichi
AU - Nakagawa, Yuko
AU - Yoshida, Yasuo
PY - 2010/3/1
Y1 - 2010/3/1
N2 - Mushrooms contain large quantities of α-glucans. Shiitake (Lentinula edodes), Japan's most popular edible mushroom, has been reported to contain about 6% (weight/dried weight) of α-(1,3)-glucan. This glucan is one of the major components of oral biofilm formed by the cariogenic bacteria Streptococcus mutans and Streptococcus sobrinus. We found that extracts from shiitake and other edible mushrooms could reduce preformed biofilms of S. mutans and S. sobrinus in the presence of dextranase. We also investigated the α-glucanase activities of shiitake mushroom extracts and their effects on biofilm formation. The extracts possessed α-glucanase activity and degraded water-insoluble glucans from mutans streptococci. The extracts strongly inhibited the sucrose-dependent formation of biofilms by S. mutans and S. sobrinus in the presence of dextranase. Our results suggest that some components of mushrooms, including α-glucanases, might inhibit the sucrose-induced formation of oral biofilms.
AB - Mushrooms contain large quantities of α-glucans. Shiitake (Lentinula edodes), Japan's most popular edible mushroom, has been reported to contain about 6% (weight/dried weight) of α-(1,3)-glucan. This glucan is one of the major components of oral biofilm formed by the cariogenic bacteria Streptococcus mutans and Streptococcus sobrinus. We found that extracts from shiitake and other edible mushrooms could reduce preformed biofilms of S. mutans and S. sobrinus in the presence of dextranase. We also investigated the α-glucanase activities of shiitake mushroom extracts and their effects on biofilm formation. The extracts possessed α-glucanase activity and degraded water-insoluble glucans from mutans streptococci. The extracts strongly inhibited the sucrose-dependent formation of biofilms by S. mutans and S. sobrinus in the presence of dextranase. Our results suggest that some components of mushrooms, including α-glucanases, might inhibit the sucrose-induced formation of oral biofilms.
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UR - http://www.scopus.com/inward/citedby.url?scp=77249159827&partnerID=8YFLogxK
U2 - 10.1007/s00253-009-2323-y
DO - 10.1007/s00253-009-2323-y
M3 - Article
C2 - 19902205
AN - SCOPUS:77249159827
VL - 86
SP - 615
EP - 623
JO - Applied Microbiology and Biotechnology
JF - Applied Microbiology and Biotechnology
SN - 0175-7598
IS - 2
ER -