Abstract
Background/Purpose The purpose of this study was to clarify the relationship between the lung to thorax transverse area ratio (L/T ratio) and the observed to expected lung area to head circumference ratio (O/E LHR), based on the results of a nationwide Japanese survey conducted in 2011, and to evaluate the compatibility of these prognostic predictors of fetal CDH. Methods Two hundred and forty-two prenatally diagnosed isolated CDH patients born between 2006 and 2010 were included in the present analysis. A regression analysis was conducted to investigate the relationship between the L/T ratio and the O/E LHR based on 191 simultaneous measurements of these parameters in 120 patients. Results The linear regression equation between the L/T ratio and the O/E LHR was: L/T ratio = 0.0233 + (0.00222 × O/E LHR), (R = 0.847, p < 0.0001). According to this equation, 25% of the O/E LHR, the cut-off value used in the fetal intervention for CDH, was equivalent to an L/T ratio of 0.08, a commonly accepted cut-off value for identifying the most severe cases of fetal CDH. Conclusions As there is a positive correlation between the L/T ratio and the O/E LHR, these two parameters proved to be used interchangeably according to the linear regression equation.
| Original language | English |
|---|---|
| Pages (from-to) | 1191-1196 |
| Number of pages | 6 |
| Journal | Journal of Pediatric Surgery |
| Volume | 49 |
| Issue number | 8 |
| DOIs | |
| Publication status | Published - Aug 2014 |
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All Science Journal Classification (ASJC) codes
- Surgery
- Pediatrics, Perinatology, and Child Health
Cite this
The lung to thorax transverse area ratio has a linear correlation with the observed to expected lung area to head circumference ratio in fetuses with congenital diaphragmatic hernias. / Usui, Noriaki; Okuyama, Hiroomi; Kanamori, Yutaka; Nagata, Kouji; Hayakawa, Masahiro; Inamura, Noboru; Takahashi, Shigehiro; Taguchi, Tomoaki.
In: Journal of Pediatric Surgery, Vol. 49, No. 8, 08.2014, p. 1191-1196.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The lung to thorax transverse area ratio has a linear correlation with the observed to expected lung area to head circumference ratio in fetuses with congenital diaphragmatic hernias
AU - Usui, Noriaki
AU - Okuyama, Hiroomi
AU - Kanamori, Yutaka
AU - Nagata, Kouji
AU - Hayakawa, Masahiro
AU - Inamura, Noboru
AU - Takahashi, Shigehiro
AU - Taguchi, Tomoaki
PY - 2014/8
Y1 - 2014/8
N2 - Background/Purpose The purpose of this study was to clarify the relationship between the lung to thorax transverse area ratio (L/T ratio) and the observed to expected lung area to head circumference ratio (O/E LHR), based on the results of a nationwide Japanese survey conducted in 2011, and to evaluate the compatibility of these prognostic predictors of fetal CDH. Methods Two hundred and forty-two prenatally diagnosed isolated CDH patients born between 2006 and 2010 were included in the present analysis. A regression analysis was conducted to investigate the relationship between the L/T ratio and the O/E LHR based on 191 simultaneous measurements of these parameters in 120 patients. Results The linear regression equation between the L/T ratio and the O/E LHR was: L/T ratio = 0.0233 + (0.00222 × O/E LHR), (R = 0.847, p < 0.0001). According to this equation, 25% of the O/E LHR, the cut-off value used in the fetal intervention for CDH, was equivalent to an L/T ratio of 0.08, a commonly accepted cut-off value for identifying the most severe cases of fetal CDH. Conclusions As there is a positive correlation between the L/T ratio and the O/E LHR, these two parameters proved to be used interchangeably according to the linear regression equation.
AB - Background/Purpose The purpose of this study was to clarify the relationship between the lung to thorax transverse area ratio (L/T ratio) and the observed to expected lung area to head circumference ratio (O/E LHR), based on the results of a nationwide Japanese survey conducted in 2011, and to evaluate the compatibility of these prognostic predictors of fetal CDH. Methods Two hundred and forty-two prenatally diagnosed isolated CDH patients born between 2006 and 2010 were included in the present analysis. A regression analysis was conducted to investigate the relationship between the L/T ratio and the O/E LHR based on 191 simultaneous measurements of these parameters in 120 patients. Results The linear regression equation between the L/T ratio and the O/E LHR was: L/T ratio = 0.0233 + (0.00222 × O/E LHR), (R = 0.847, p < 0.0001). According to this equation, 25% of the O/E LHR, the cut-off value used in the fetal intervention for CDH, was equivalent to an L/T ratio of 0.08, a commonly accepted cut-off value for identifying the most severe cases of fetal CDH. Conclusions As there is a positive correlation between the L/T ratio and the O/E LHR, these two parameters proved to be used interchangeably according to the linear regression equation.
UR - http://www.scopus.com/inward/record.url?scp=84905494333&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84905494333&partnerID=8YFLogxK
U2 - 10.1016/j.jpedsurg.2013.10.021
DO - 10.1016/j.jpedsurg.2013.10.021
M3 - Article
C2 - 25092074
AN - SCOPUS:84905494333
VL - 49
SP - 1191
EP - 1196
JO - Journal of Pediatric Surgery
JF - Journal of Pediatric Surgery
SN - 0022-3468
IS - 8
ER -