The majority of cDNA clones with strong positive signals for the interferon-induction-specific sequences resemble mitochondrial ribosomal RNA genes

Teruhisa Tsuzuki, Hisayuki Nomiyama, Chiaki Setoyama, Shuichiro Maeda, Kazunori Shimada, Sidney Pestka

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

A complementary DNA library prepared from the 12S polyadenylated RNAs extracted from interferon-induced KG-1 cells, a human myeloblast cell line, was screened for the presence of induction-specific sequences. Clones that exhibited strong positive signals were separated by hybridization criteria into nine classes. Clones from classes I through IV consisted of about 78% of the total and unexpectedly were found to resemble human mitochondrial ribosomal RNA genes.

Original languageEnglish
Pages (from-to)670-676
Number of pages7
JournalBiochemical and Biophysical Research Communications
Volume114
Issue number2
DOIs
Publication statusPublished - Jul 29 1983

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology

Fingerprint Dive into the research topics of 'The majority of cDNA clones with strong positive signals for the interferon-induction-specific sequences resemble mitochondrial ribosomal RNA genes'. Together they form a unique fingerprint.

  • Cite this