The meaning of FDG PET-CT and sentinel lymph node biopsy in patients with cN0 oral squamous cell carcinoma

Takayoshi Aramoto, Koh ichi Nakashiro, Hidetomo Nishikawa, Masao Miyagawa, Hiroyuki Hamakawa, Tomoki Sumida

Research output: Contribution to journalArticle

Abstract

Recently, FDG PET-CT has been widely applied to examine the primary region of malignant tumor and metastasis to the lymph nodes or distant organs. Here, we investigated the usefulness of FDG PET-CT and sentinel lymph node biopsy in patients with cN0 oral squamous cell carcinoma. The scope of this study was 43 sentinel lymph nodes from 23 patients with oral squamous cell carcinoma in whom lymph node metastasis was not detected by traditional imaging, and who were examined by FDG PET-CT. After the sentinel lymph nodes were identified and resected, we evaluated the presence of metastasis in them histopathologically. As a result, in 43 lymph nodes, we detected metastases in 4 lymph nodes from 4 patients, but only 1 lymph node from 1 patient was detected by FDG PET-CT. These results suggest that FDG PET-CT and traditional imaging may have limited accuracy for diagnosing cervical lymph node metastasis, and that sentinel lymph node biopsy is also necessary.

Original languageEnglish
Pages (from-to)513-517
Number of pages5
JournalToukeibu Gan
Volume34
Issue number4
DOIs
Publication statusPublished - Jan 1 2008

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All Science Journal Classification (ASJC) codes

  • Otorhinolaryngology
  • Oncology

Cite this

Aramoto, T., Nakashiro, K. I., Nishikawa, H., Miyagawa, M., Hamakawa, H., & Sumida, T. (2008). The meaning of FDG PET-CT and sentinel lymph node biopsy in patients with cN0 oral squamous cell carcinoma. Toukeibu Gan, 34(4), 513-517. https://doi.org/10.5981/jjhnc.34.513