The modification of RGD peptides to PKA signal responsive Polymer and the evaluation of its function

Moeko Ijuin, Jun Oishi, Kenji Kawamura, Jeong Hun Kang, Daisuke Asai, Yuko Sato, Yoshiki Katayama

    Research output: Contribution to conferencePaperpeer-review

    Abstract

    We recently proposed the novel gene-regulation polymer responding to cAMP-dependent protein kinase (PKA). However this polymer alone only had poor ability for the gene delivery into living cells. Thus it is difficult to evaluate the function of this polymer in living cells. On the other hand, it has been reported Arg-Gly-Asp (RGD) peptides modified polymer was efficiently deliveried genes into cells. In the present study, we modified the signal responsive polymer to RGD peptide for the introduction of polymer-DNA complex into living cells.

    Original languageEnglish
    Number of pages1
    Publication statusPublished - Oct 19 2006
    Event55th SPSJ Annual Meeting - Nagoya, Japan
    Duration: May 24 2006May 26 2006

    Other

    Other55th SPSJ Annual Meeting
    Country/TerritoryJapan
    CityNagoya
    Period5/24/065/26/06

    All Science Journal Classification (ASJC) codes

    • Engineering(all)

    Fingerprint

    Dive into the research topics of 'The modification of RGD peptides to PKA signal responsive Polymer and the evaluation of its function'. Together they form a unique fingerprint.

    Cite this