The mucin box and signal/anchor sequence of rat neutral ceramidase recruit bacterial sphingomyelinase to the plasma membrane

Tetsuto Nakagawa, Motohiro Tani, Noriyuki Sueyoshi, Makoto Ito

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Sphingolipid metabolites act as lipid mediators in various cellular events. We found that the mucin box and signal/anchor sequence of a rat neutral ceramidase recruit bacterial sphingomyelinase to the plasma membranes of mammalian cells. The mucin box-fused sphingomyelinase hydrolyzed cellular sphingomyelin efficiently to generate ceramide.

Original languageEnglish
Pages (from-to)987-990
Number of pages4
JournalBioscience, Biotechnology and Biochemistry
Volume75
Issue number5
DOIs
Publication statusPublished - Jun 6 2011

Fingerprint

Neutral Ceramidase
Sphingomyelin Phosphodiesterase
Mucins
Cell membranes
Protein Sorting Signals
Anchors
Rats
Cell Membrane
Sphingolipids
Sphingomyelins
Ceramides
Metabolites
Cells
Lipids

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Analytical Chemistry
  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Molecular Biology
  • Organic Chemistry

Cite this

The mucin box and signal/anchor sequence of rat neutral ceramidase recruit bacterial sphingomyelinase to the plasma membrane. / Nakagawa, Tetsuto; Tani, Motohiro; Sueyoshi, Noriyuki; Ito, Makoto.

In: Bioscience, Biotechnology and Biochemistry, Vol. 75, No. 5, 06.06.2011, p. 987-990.

Research output: Contribution to journalArticle

@article{53a34d863751429db51902a4398daa7a,
title = "The mucin box and signal/anchor sequence of rat neutral ceramidase recruit bacterial sphingomyelinase to the plasma membrane",
abstract = "Sphingolipid metabolites act as lipid mediators in various cellular events. We found that the mucin box and signal/anchor sequence of a rat neutral ceramidase recruit bacterial sphingomyelinase to the plasma membranes of mammalian cells. The mucin box-fused sphingomyelinase hydrolyzed cellular sphingomyelin efficiently to generate ceramide.",
author = "Tetsuto Nakagawa and Motohiro Tani and Noriyuki Sueyoshi and Makoto Ito",
year = "2011",
month = "6",
day = "6",
doi = "10.1271/bbb.100767",
language = "English",
volume = "75",
pages = "987--990",
journal = "Bioscience, Biotechnology and Biochemistry",
issn = "0916-8451",
publisher = "Japan Society for Bioscience Biotechnology and Agrochemistry",
number = "5",

}

TY - JOUR

T1 - The mucin box and signal/anchor sequence of rat neutral ceramidase recruit bacterial sphingomyelinase to the plasma membrane

AU - Nakagawa, Tetsuto

AU - Tani, Motohiro

AU - Sueyoshi, Noriyuki

AU - Ito, Makoto

PY - 2011/6/6

Y1 - 2011/6/6

N2 - Sphingolipid metabolites act as lipid mediators in various cellular events. We found that the mucin box and signal/anchor sequence of a rat neutral ceramidase recruit bacterial sphingomyelinase to the plasma membranes of mammalian cells. The mucin box-fused sphingomyelinase hydrolyzed cellular sphingomyelin efficiently to generate ceramide.

AB - Sphingolipid metabolites act as lipid mediators in various cellular events. We found that the mucin box and signal/anchor sequence of a rat neutral ceramidase recruit bacterial sphingomyelinase to the plasma membranes of mammalian cells. The mucin box-fused sphingomyelinase hydrolyzed cellular sphingomyelin efficiently to generate ceramide.

UR - http://www.scopus.com/inward/record.url?scp=79957801844&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79957801844&partnerID=8YFLogxK

U2 - 10.1271/bbb.100767

DO - 10.1271/bbb.100767

M3 - Article

C2 - 21597176

AN - SCOPUS:79957801844

VL - 75

SP - 987

EP - 990

JO - Bioscience, Biotechnology and Biochemistry

JF - Bioscience, Biotechnology and Biochemistry

SN - 0916-8451

IS - 5

ER -