The pathway of leucine to mevalonate in halophilic archaea: Efficient incorporation of leucine into isoprenoidal lipid with the involvement of isovaleryl-CoA dehydrogenase in halobacterium salinarum

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)

Abstract

The pathway of leucine to mevalonate, which has attracted attention in the study of the biosynthesis of isoprenoid in parasitic protozoa and myxobacterium, was observed in the biosynthesis of the lipid core in halophilic archaea. The involvement of isovaleryl-CoA dehydrogenase was strongly suggested, with stereospecific conversion of the diastereotopic methyl group of leucine to isoprenoidal lipid.

Original languageEnglish
Pages (from-to)443-446
Number of pages4
JournalBioscience, Biotechnology and Biochemistry
Volume74
Issue number2
DOIs
Publication statusPublished - Mar 1 2010

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Analytical Chemistry
  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Molecular Biology
  • Organic Chemistry

Fingerprint Dive into the research topics of 'The pathway of leucine to mevalonate in halophilic archaea: Efficient incorporation of leucine into isoprenoidal lipid with the involvement of isovaleryl-CoA dehydrogenase in halobacterium salinarum'. Together they form a unique fingerprint.

Cite this