The effect of dosing time on salicylic acid (SA) kinetics after single oral administrations of two different aspirin formulations, a slow-release tablet (Verin®) and enteric-coated granules (Minimax), was investigated in 15 healthy Japanese men. Eight subjects received slow-release tablets and the other seven subjects received enteric-coated granules. Each aspirin formulation was given in the morning (8 : 30) or in the evening (20 : 30) in a randomly assigned cross-over study. After the single dose study, the SA kinetics following repeated administration of the two different aspirin.
|Number of pages||10|
|Journal||Japanese Journal of Clinical Pharmacology and Therapeutics|
|Publication status||Published - 1985|
All Science Journal Classification (ASJC) codes
- Pharmacology (medical)