Abstract
The point of this study was to examine the presence or absence of cytokine-positive cells by means of immunohistochemical methods in the samples of inflamed gingival tissues obtained from an 11-year-old girl with Papillon-Lefevre syndrome (PLS). Interleukin-8 (IL-8)-positive cells were found to be present. In addition, IL-1α-and IL-1β-positive cells were detected. No dysfunction in the phagocytosis and the bacterial killing of peripheral blood polymorphonuclear neutrophils (PMNs) was observed in this patient. Our findings suggest that these cytokines may be members responsible for modulating the process of rapidly progressive periodontitis for patient with PLS.
| Original language | English |
|---|---|
| Pages (from-to) | 121-126 |
| Number of pages | 6 |
| Journal | Cytokine |
| Volume | 18 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - Jan 1 2002 |
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All Science Journal Classification (ASJC) codes
- Immunology and Allergy
- Immunology
- Biochemistry
- Hematology
- Molecular Biology
Cite this
The presence of cytokine (IL-8, IL-1α, IL-1β)-producing cells in inflamed gingival tissue from a patient manifesting papillon-lefevre syndrome (PLS). / Kabashima, Hiroaki; Yoneda, Masahiro; Nagata, Kengo; Nonaka, Kazuaki; Hirofuji, Takao; Maeda, Katsumasa.
In: Cytokine, Vol. 18, No. 3, 01.01.2002, p. 121-126.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The presence of cytokine (IL-8, IL-1α, IL-1β)-producing cells in inflamed gingival tissue from a patient manifesting papillon-lefevre syndrome (PLS)
AU - Kabashima, Hiroaki
AU - Yoneda, Masahiro
AU - Nagata, Kengo
AU - Nonaka, Kazuaki
AU - Hirofuji, Takao
AU - Maeda, Katsumasa
PY - 2002/1/1
Y1 - 2002/1/1
N2 - The point of this study was to examine the presence or absence of cytokine-positive cells by means of immunohistochemical methods in the samples of inflamed gingival tissues obtained from an 11-year-old girl with Papillon-Lefevre syndrome (PLS). Interleukin-8 (IL-8)-positive cells were found to be present. In addition, IL-1α-and IL-1β-positive cells were detected. No dysfunction in the phagocytosis and the bacterial killing of peripheral blood polymorphonuclear neutrophils (PMNs) was observed in this patient. Our findings suggest that these cytokines may be members responsible for modulating the process of rapidly progressive periodontitis for patient with PLS.
AB - The point of this study was to examine the presence or absence of cytokine-positive cells by means of immunohistochemical methods in the samples of inflamed gingival tissues obtained from an 11-year-old girl with Papillon-Lefevre syndrome (PLS). Interleukin-8 (IL-8)-positive cells were found to be present. In addition, IL-1α-and IL-1β-positive cells were detected. No dysfunction in the phagocytosis and the bacterial killing of peripheral blood polymorphonuclear neutrophils (PMNs) was observed in this patient. Our findings suggest that these cytokines may be members responsible for modulating the process of rapidly progressive periodontitis for patient with PLS.
UR - http://www.scopus.com/inward/record.url?scp=0035997260&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0035997260&partnerID=8YFLogxK
U2 - 10.1006/cyto.2002.1005
DO - 10.1006/cyto.2002.1005
M3 - Article
C2 - 12126647
AN - SCOPUS:0035997260
VL - 18
SP - 121
EP - 126
JO - Cytokine
JF - Cytokine
SN - 1043-4666
IS - 3
ER -