The proposal of a neuron model in consideration of facilitation and fatigue

Sheng Ge, M. Ichikawa, A. Osa, H. Miike, K. Iramina

Research output: Contribution to journalConference article


In the past research on the neural transform model, some researchers took both excitation and inhibition factors into consideration. However, these past models relate to diffusion of the substance between neighboring cells, therefore these models are not rational for considering both excitation and inhibition factors in a separate cell. When repeated stimulation depolarizes a presynaptic axon terminal, the level of Ca2+ in the presynaptic axon terminal is increased. Thus, an increased number of quanta of transmitter are released. On the other hand, the release of the transmitter will result in the decrease in the quantity of the transmitter in the presynaptic axon terminal. Based on these physiology characteristics of synaptic transmission, we propose a new model in which facilitation and fatigue are both considered in a separate cell. Using the proposed model, short-term memory process, image feature detection and other image processing were simulated. We suggest that the proposed model is a valid and widely applicable neural model.

Original languageEnglish
Pages (from-to)142-144
Number of pages3
JournalIFMBE Proceedings
Issue number1
Publication statusPublished - Jan 1 2007
Event10th World Congress on Medical Physics and Biomedical Engineering, WC 2006 - Seoul, Korea, Republic of
Duration: Aug 27 2006Sep 1 2006


All Science Journal Classification (ASJC) codes

  • Bioengineering
  • Biomedical Engineering

Cite this