The relation of coffee consumption to serum uric acid in Japanese men and women aged 49-76 years

Ngoc Minh Pham, Daigo Yoshida, Makiko Morita, Guang Yin, Kengo Toyomura, Ohnaka Keizo, Ryoichi Takayanagi, Suminori Kono

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

Objective. Few studies have suggested an inverse relation between coffee intake and serum concentrations of uric acid (UA), but none has addressed the relation in men and women separately. We examined the relation between coffee intake and serum UA levels in free-living middle-aged and elderly men and women in Fukuoka, Japan. Methods. Study subjects were derived from the baseline survey of a cohort study on lifestyle-related diseases, and included 11.662 men and women aged 49-76 years; excluded were those with medication for gout and hyperuricemia, use of diuretic drugs, and medical care for cancer or chronic kidney disease. Statistical adjustment was made for body mass index, alcohol use, hypertension, diabetes mellitus, and other factors. Results. There were inverse associations of coffee consumption with serum UA concentrations and hyperuricemia in men regardless of adjustment for covariates. Women showed a statistically significant, but weaker, inverse association between coffee and serum UA levels after allowance for the confounding factors. Conclusion. The findings add to evidence for a protective association between coffee intake and hyperuricemia.

Original languageEnglish
Article number930757
JournalJournal of Nutrition and Metabolism
Volume2010
DOIs
Publication statusPublished - Dec 1 2010

Fingerprint

hyperuricemia
Coffee
uric acid
Uric Acid
Hyperuricemia
Serum
middle-aged adults
gout
diuretics
Social Adjustment
diabetes mellitus
kidney diseases
cohort studies
Gout
hypertension
drug therapy
lifestyle
body mass index
Chronic Renal Insufficiency
Diuretics

All Science Journal Classification (ASJC) codes

  • Endocrinology, Diabetes and Metabolism
  • Food Science
  • Nutrition and Dietetics

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The relation of coffee consumption to serum uric acid in Japanese men and women aged 49-76 years. / Pham, Ngoc Minh; Yoshida, Daigo; Morita, Makiko; Yin, Guang; Toyomura, Kengo; Keizo, Ohnaka; Takayanagi, Ryoichi; Kono, Suminori.

In: Journal of Nutrition and Metabolism, Vol. 2010, 930757, 01.12.2010.

Research output: Contribution to journalArticle

Pham, Ngoc Minh ; Yoshida, Daigo ; Morita, Makiko ; Yin, Guang ; Toyomura, Kengo ; Keizo, Ohnaka ; Takayanagi, Ryoichi ; Kono, Suminori. / The relation of coffee consumption to serum uric acid in Japanese men and women aged 49-76 years. In: Journal of Nutrition and Metabolism. 2010 ; Vol. 2010.
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AU - Morita, Makiko

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AU - Toyomura, Kengo

AU - Keizo, Ohnaka

AU - Takayanagi, Ryoichi

AU - Kono, Suminori

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