The relationship between three signs of fetal magnetic resonance imaging and severity of congenital diaphragmatic hernia

T. Hattori, M. Hayakawa, M. Ito, Y. Sato, K. Tamakoshi, Y. Kanamori, H. Okuyama, N. Inamura, S. Takahashi, Y. Fujino, Tomoaki Taguchi, N. Usui

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Objective:To seek a simple approach for prenatally classifying congenital diaphragmatic hernia (CDH) severity using fetal magnetic resonance imaging (MRI) markers.Study design:A retrospective, multicenter study using questionnaires to investigate fetal MRI findings. We included fetuses prenatally diagnosed with isolated left-sided CDH and delivered after 36 weeks of gestation. We focused on three fetal MRI morphological signs: incomplete pulmonary baseline (IPB), liver up (LU) and retrocardiac stomach (RCS). We also evaluated the fetal MRI score defined as the total number of positive signs; the primary outcome was survival at discharge.Results:In 256 patients (from 56 institutions), IPB, LU and RCS findings correlated with lower survival: odds ratio (95% confidence interval), 0.16 (0.08 to 0.33); 0.24 (0.12 to 0.51); and 0.14 (0.07 to 0.28); respectively. Patients with higher fetal MRI scores had a higher mortality rate.Conclusion:IPB, LU and RCS on fetal MRI are related to CDH severity.

Original languageEnglish
Pages (from-to)265-269
Number of pages5
JournalJournal of Perinatology
Volume37
Issue number3
DOIs
Publication statusPublished - Mar 1 2017

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Magnetic Resonance Imaging
Stomach
Lung
Liver
Survival
Multicenter Studies
Congenital Diaphragmatic Hernias
Fetus
Retrospective Studies
Odds Ratio
Confidence Intervals
Pregnancy
Mortality

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynaecology

Cite this

The relationship between three signs of fetal magnetic resonance imaging and severity of congenital diaphragmatic hernia. / Hattori, T.; Hayakawa, M.; Ito, M.; Sato, Y.; Tamakoshi, K.; Kanamori, Y.; Okuyama, H.; Inamura, N.; Takahashi, S.; Fujino, Y.; Taguchi, Tomoaki; Usui, N.

In: Journal of Perinatology, Vol. 37, No. 3, 01.03.2017, p. 265-269.

Research output: Contribution to journalArticle

Hattori, T, Hayakawa, M, Ito, M, Sato, Y, Tamakoshi, K, Kanamori, Y, Okuyama, H, Inamura, N, Takahashi, S, Fujino, Y, Taguchi, T & Usui, N 2017, 'The relationship between three signs of fetal magnetic resonance imaging and severity of congenital diaphragmatic hernia', Journal of Perinatology, vol. 37, no. 3, pp. 265-269. https://doi.org/10.1038/jp.2016.208
Hattori, T. ; Hayakawa, M. ; Ito, M. ; Sato, Y. ; Tamakoshi, K. ; Kanamori, Y. ; Okuyama, H. ; Inamura, N. ; Takahashi, S. ; Fujino, Y. ; Taguchi, Tomoaki ; Usui, N. / The relationship between three signs of fetal magnetic resonance imaging and severity of congenital diaphragmatic hernia. In: Journal of Perinatology. 2017 ; Vol. 37, No. 3. pp. 265-269.
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