The relationship of duration and pain with the infiltration anesthesia to the presense or absense of topical anesthesia

O. Nakanishi, T. Ishii, T. Hirakawa, Eiji Sakamoto, T. Ishikawa, F. Kou, H. Fuushuku, Y. Imamura, M. Nishi

Research output: Contribution to journalArticle


The relation of the duration of injection and the activity of topical anesthesia for the injection pain of infilitration anesthesia were examined by using a visual analog scale (VAS) in eighteen healthy volunteers (Table 1). Topical anesthesia (5% benzocaine, Hurricaine®, Beutlich, Inc.) or placebo was applied at the mucobuccal region of the canine. The injection pain of infiltration anesthesia was assessed with 20 second (20 sec group), 40 second (40 sec group), and 60 second duration (60 sec group) at the mucobuccal region of the canine at 1.5 minutes after applying the topical anesthesia or placebo (Fig. 1). In the comparision of VAS in the placebo groups, the 40 and 60 sec groups showed almost the same value, but the 20 sec group was higher. In the topical anesthesia group, the value of VAS was decreased in order by the length of the duration of the injection. Between the topical anesthesia, and placebo groups, there were no significant differences within each duration. However, there were significant differences between the 20 sec group without topical anesthesia and the 60 sec duration group with topical anesthesia in injection pain (Fig. 2). In both groups, there were no significant differences in blood pressure and heart rate before, during, or after injection (Table 2). These results indicate that an injection of 40 second duration in enough to inject 0.9 ml of infiltration anesthesic and the VAS value of 60 seconds injection of 0.9 ml infiltration anesthetic is lower than the other groups value in the case of 90 seconds from application of topical anesthesia to infiltration anesthetic.

Original languageEnglish
Pages (from-to)50-54
Number of pages5
JournalJournal of Japanese Dental Society of Anesthesiology
Issue number1
Publication statusPublished - Mar 4 1996
Externally publishedYes


All Science Journal Classification (ASJC) codes

  • Dentistry(all)
  • Anesthesiology and Pain Medicine

Cite this