The role of coagulopathy in the pathogenesis and prevention of corticosteroid-induced osteonecrosis

Takuaki Yamamoto; goro motomura; Ryosuke Yamaguchi; Yukihide Iwamoto

doi:10.1007/978-3-642-35767-1_33

The role of coagulopathy in the pathogenesis and prevention of corticosteroid-induced osteonecrosis

Takuaki Yamamoto, goro motomura, Ryosuke Yamaguchi, Yukihide Iwamoto

Orthopedic Surgery

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

In nontraumatic osteonecrosis (ON) of the femoral head, several abnormalities in the coagulation-fi brinolysis system have been reported, including increase of plasminogen activator inhibitor-1 level [ 1 ], the presence of antiphospholipid antibodies [ 2 ], familial heterozygous protein S defi ciency [ 3 ], and antithrombin III defi ciency [ 4 ]. These abnormalities are thought to induce hypercoagulability in the blood vessels.

Original language	English
Title of host publication	Osteonecrosis
Publisher	Springer Berlin Heidelberg
Pages	249-253
Number of pages	5
ISBN (Electronic)	9783642357671
ISBN (Print)	9783642357664
DOIs	https://doi.org/10.1007/978-3-642-35767-1_33
Publication status	Published - Jan 1 2014

All Science Journal Classification (ASJC) codes

Medicine(all)

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10.1007/978-3-642-35767-1_33

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AU - Iwamoto, Yukihide

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AB - In nontraumatic osteonecrosis (ON) of the femoral head, several abnormalities in the coagulation-fi brinolysis system have been reported, including increase of plasminogen activator inhibitor-1 level [ 1 ], the presence of antiphospholipid antibodies [ 2 ], familial heterozygous protein S defi ciency [ 3 ], and antithrombin III defi ciency [ 4 ]. These abnormalities are thought to induce hypercoagulability in the blood vessels.

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The role of coagulopathy in the pathogenesis and prevention of corticosteroid-induced osteonecrosis

Abstract

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