TY - JOUR
T1 - The role of hematopoietic stem cell transplantation for acute myeloid leukemia
AU - Kato, Koji
N1 - Copyright:
This record is sourced from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
PY - 2015/10/1
Y1 - 2015/10/1
N2 - Hematopoietic stem cell transplantation (HSCT) plays an important role in treating younger patients with acute myeloid leukemia (AML). Reduced-intensity conditioning regimens allow increased use of allogeneic HSCT for older patients. Current HSCT decisions in patients with AML are being made according to cytogenetic analysis results. A more comprehensive and detailed understanding of the genetic and epigenetic changes that are related to the pathogenesis of AML is required for better classification of risk and for improving approaches to therapy as they pertain to future HSCT decisions.
AB - Hematopoietic stem cell transplantation (HSCT) plays an important role in treating younger patients with acute myeloid leukemia (AML). Reduced-intensity conditioning regimens allow increased use of allogeneic HSCT for older patients. Current HSCT decisions in patients with AML are being made according to cytogenetic analysis results. A more comprehensive and detailed understanding of the genetic and epigenetic changes that are related to the pathogenesis of AML is required for better classification of risk and for improving approaches to therapy as they pertain to future HSCT decisions.
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U2 - 10.11406/rinketsu.56.1950
DO - 10.11406/rinketsu.56.1950
M3 - Article
C2 - 26458433
AN - SCOPUS:84986556327
SN - 0485-1439
VL - 56
SP - 1950
EP - 1959
JO - [Rinsho ketsueki] The Japanese journal of clinical hematology
JF - [Rinsho ketsueki] The Japanese journal of clinical hematology
IS - 10
ER -