TY - JOUR
T1 - The role of interleukin 15 in mounting an immune response against microbial infections
AU - Yoshikai, Yasunobu
AU - Nishimura, Hitoshi
PY - 2000/4
Y1 - 2000/4
N2 - Interleukin (IL)-15 is a recently described cytokine that resembles IL-2 in its biological activities, stimulating natural killer cells, T cells and B cells to proliferate, secrete cytokines, and exhibit increased cytotoxicities or produce antibody IL-15 also exerts unique functions such as stimulation of phagocytes, maintenance of mast cells and migration of activated/memory T cells. IL-15 is involved in protection against infections with a variety of microbes through not only activating innate immunity but also mounting adaptive immunity. (C) 2000 Editions scientifiques et medicales Elsevier SAS.
AB - Interleukin (IL)-15 is a recently described cytokine that resembles IL-2 in its biological activities, stimulating natural killer cells, T cells and B cells to proliferate, secrete cytokines, and exhibit increased cytotoxicities or produce antibody IL-15 also exerts unique functions such as stimulation of phagocytes, maintenance of mast cells and migration of activated/memory T cells. IL-15 is involved in protection against infections with a variety of microbes through not only activating innate immunity but also mounting adaptive immunity. (C) 2000 Editions scientifiques et medicales Elsevier SAS.
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U2 - 10.1016/S1286-4579(00)00329-4
DO - 10.1016/S1286-4579(00)00329-4
M3 - Review article
C2 - 10817640
AN - SCOPUS:0034095297
SN - 1286-4579
VL - 2
SP - 381
EP - 389
JO - Microbes and Infection
JF - Microbes and Infection
IS - 4
ER -
