The significance of peritoneal cytology in uterine cervix and endometrial cancer

Masamichi Kashimura, Koichiro Sugihara, Naoyuki Toki, Yusuke Matsuura, Toshinori Kawagoe, Toshiharu Kamura, Tsunehisa Kaku, Nobuhiro Tsuruchi, Hisayoshi Nakashima, Hidetaka Sakai

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Abstract

Objective. The purpose of this study was to determine the incidence of positive peritoneal cytology and to elucidate the prognostic value of peritoneal cytology in patients with uterine cervix and endometrial cancer. Materials and methods. The incidence of positive peritoneal cytology was investigated in 642 patients including 339 uterine cervix and 303 endometrial cancers. Survival was estimated by the Kaplan-Meier method in a subgroup of 116 stage II cervix and 199 stage I endometrial cancers, and multivariate analysis using Cox's proportional hazards model was used to identify an independent prognostic factor. Results. The incidence of positive peritoneal cytology was found to be 9% in uterine cervix cancer and 15% in endometrial cancer. The incidence was higher in patients with some clinicopathologic status such as advanced stage, lymph node metastasis, ovarian metastasis, and deeper myometrial invasion. The 5-year survival rate for patients with positive or negative peritoneal cytology was 44 or 80% in stage II cervix cancers and 80 or 92% in clinical stage I endometrial cancers, respectively. Multivariate analysis revealed that independent prognostic determinants were pelvic and paraaortic lymph node metastasis and peritoneal cytology in stage II cervix cancer and peritoneal cytology in stage I endometrial cancer. Proper treatment protocol should be scheduled for patients with positive peritoneal cytology.

Original languageEnglish
Pages (from-to)285-290
Number of pages6
JournalGynecologic Oncology
Volume67
Issue number3
DOIs
Publication statusPublished - Jan 1 1997

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Uterine Neoplasms
Endometrial Neoplasms
Cervix Uteri
Uterine Cervical Neoplasms
Cell Biology
Incidence
Neoplasm Metastasis
Multivariate Analysis
Lymph Nodes
Clinical Protocols
Proportional Hazards Models
Survival Rate
Survival

All Science Journal Classification (ASJC) codes

  • Oncology
  • Obstetrics and Gynaecology

Cite this

Kashimura, M., Sugihara, K., Toki, N., Matsuura, Y., Kawagoe, T., Kamura, T., ... Sakai, H. (1997). The significance of peritoneal cytology in uterine cervix and endometrial cancer. Gynecologic Oncology, 67(3), 285-290. https://doi.org/10.1006/gyno.1997.4858

The significance of peritoneal cytology in uterine cervix and endometrial cancer. / Kashimura, Masamichi; Sugihara, Koichiro; Toki, Naoyuki; Matsuura, Yusuke; Kawagoe, Toshinori; Kamura, Toshiharu; Kaku, Tsunehisa; Tsuruchi, Nobuhiro; Nakashima, Hisayoshi; Sakai, Hidetaka.

In: Gynecologic Oncology, Vol. 67, No. 3, 01.01.1997, p. 285-290.

Research output: Contribution to journalArticle

Kashimura, M, Sugihara, K, Toki, N, Matsuura, Y, Kawagoe, T, Kamura, T, Kaku, T, Tsuruchi, N, Nakashima, H & Sakai, H 1997, 'The significance of peritoneal cytology in uterine cervix and endometrial cancer', Gynecologic Oncology, vol. 67, no. 3, pp. 285-290. https://doi.org/10.1006/gyno.1997.4858
Kashimura M, Sugihara K, Toki N, Matsuura Y, Kawagoe T, Kamura T et al. The significance of peritoneal cytology in uterine cervix and endometrial cancer. Gynecologic Oncology. 1997 Jan 1;67(3):285-290. https://doi.org/10.1006/gyno.1997.4858
Kashimura, Masamichi ; Sugihara, Koichiro ; Toki, Naoyuki ; Matsuura, Yusuke ; Kawagoe, Toshinori ; Kamura, Toshiharu ; Kaku, Tsunehisa ; Tsuruchi, Nobuhiro ; Nakashima, Hisayoshi ; Sakai, Hidetaka. / The significance of peritoneal cytology in uterine cervix and endometrial cancer. In: Gynecologic Oncology. 1997 ; Vol. 67, No. 3. pp. 285-290.
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