The usefulness of thiosulfate as an indicator of hydrogen sulfide poisoning: Three cases

S. Kage, K. Takekawa, K. Kurosaki, T. Imamura, K. Kudo

Research output: Contribution to journalArticle

60 Citations (Scopus)

Abstract

We examined the usefulness of thiosulfate as an indicator of hydrogen sulfide poisoning by analysing sulfide and thiosulfate in three cases. In the first (non-fatal) case sulfide and thiosulfate were not detected in the blood samples from any of the four workers involved in the accident. In the urine samples, only thiosulfate was detected in three out of the four workers at a concentration of 0.12-0.43 μmol/ml, which was 4-14 times higher than the level in a healthy person. In the second (fatal) case sulfide and thiosulfate were detected in the blood sample at concentrations of 0.007 μmol/ml for sulfide, and 0.025 μmol/ml for thiosulfate. The thiosulfate concentration was at least 8 times higher than the level in a healthy person. In the third (fatal) case sulfide and thiosulfate were detected in the blood sample at concentrations of 0.95 μmol/ml for sulfide, and 0.12 μmol/ml for thiosulfate. Based on the above results, we concluded that thiosulfate in urine is the only indicator to prove hydrogen sulfide poisoning in non-fatal cases, while the analysis of sulfide in fatal cases should be accompanied by the measurement of thiosulfate in blood.

Original languageEnglish
Pages (from-to)220-222
Number of pages3
JournalInternational Journal of Legal Medicine
Volume110
Issue number4
DOIs
Publication statusPublished - Aug 1 1997

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine

Fingerprint Dive into the research topics of 'The usefulness of thiosulfate as an indicator of hydrogen sulfide poisoning: Three cases'. Together they form a unique fingerprint.

  • Cite this