Thermal cyclization of nonconjugated aryl-yne-carbodiimide furnishing a dibenzonaphthyridine derivative

Hidenori Kimura, Kohei Torikai, Ikuo Ueda

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)

Abstract

The reagent-free C2-C7 thermal cyclization of a nonconjugated aryl-yne-carbodiimide yielded a dibenzo- [b,g][1,8]naphthyridine derivative, whose congeners are known to possess fascinating pharmacological properties. This is the first heteroaromatic compound prepared by the thermal cycloaromatization of "nonconjugated" aryl-ynes.

Original languageEnglish
Pages (from-to)393-396
Number of pages4
JournalChemical and Pharmaceutical Bulletin
Volume57
Issue number4
DOIs
Publication statusPublished - 2009
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Drug Discovery

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