Thermally tunable deterministic lateral displacement through hydrogel micro pillar arrays

N. Tottori, Y. Sakurai, T. Nisisako, Y. Yanagida, T. Hatsuzawa

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We present a novel deterministic lateral displacement (DLD) microfluidic device with thermally tunable separation capability. To flexibly change the critical diameter (Dc) of the separation array, we fabricated DLD micropillars made of poly-N-isopropylacrylamide, a thermo-responsive hydrogel, in a polydimethyl siloxane microfluidic channel. The prepared DLD pillars shrunk at a high temperature (>30°C) and swelled at a low temperature (<30°C) in an aqueous solution because of their characteristic hydrophilic-hydrophobic phase transitions. By heating and cooling the DLD device across the transition temperature, the Dccould be continuously changed and the separation mode of the model particles could be switched.

Original languageEnglish
Title of host publication20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
PublisherChemical and Biological Microsystems Society
Pages140-141
Number of pages2
ISBN (Electronic)9780979806490
Publication statusPublished - Jan 1 2016
Externally publishedYes
Event20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 - Dublin, Ireland
Duration: Oct 9 2016Oct 13 2016

Publication series

Name20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016

Other

Other20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
CountryIreland
CityDublin
Period10/9/1610/13/16

All Science Journal Classification (ASJC) codes

  • Control and Systems Engineering

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  • Cite this

    Tottori, N., Sakurai, Y., Nisisako, T., Yanagida, Y., & Hatsuzawa, T. (2016). Thermally tunable deterministic lateral displacement through hydrogel micro pillar arrays. In 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 (pp. 140-141). (20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016). Chemical and Biological Microsystems Society.