Abstract
The conjugate between 20-mer antisense oligodeoxynucleotides (ODN) and thermo-responsive polymer, poly(N-isopropylacrylamide) (PNIPAAm), was prepared. Hybridization reaction between the conjugate and their target RNA was modulated by conformational change of polymer moiety depending on temperature condition.
Original language | English |
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Pages (from-to) | 266-267 |
Number of pages | 2 |
Journal | Chemistry Letters |
Volume | 32 |
Issue number | 3 |
DOIs | |
Publication status | Published - Mar 5 2003 |
All Science Journal Classification (ASJC) codes
- Chemistry(all)