Thermodynamics for the Formation of Double-Stranded DNA-Single-Walled Carbon Nanotube Hybrids

Tomohiro Shiraki, Akiko Tsuzuki, Fumiyuki Toshimitsu, Naotoshi Nakashima

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)

Abstract

For the first time, the thermodynamics are described for the formation of double-stranded DNA (ds-DNA)-single-walled carbon nanotube (SWNT) hybrids. This treatment is applied to the exchange reaction of sodium cholate (SC) molecules on SWNTs and the ds-DNAs d(A)20-d(T)20 and nuclear factor (NF)-κB decoy. UV/Vis/near-IR spectroscopy with temperature variations was used for analyzing the exchange reaction on the SWNTs with four different chiralities: (n,m)=(8,3), (6,5), (7,5), and (8,6). Single-stranded DNAs (ss-DNAs), including d(A)20 and d(T)20, are also used for comparison. The d(A)20-d(T)20 shows a drastic change in its thermodynamic parameters around the melting temperature (Tm) of the DNA oligomer. No such Tm dependency was measured, owing to high Tm in the NF-κB decoy DNA and no Tm in the ss-DNA.

Original languageEnglish
Pages (from-to)4774-4779
Number of pages6
JournalChemistry - A European Journal
Volume22
Issue number14
DOIs
Publication statusPublished - Mar 24 2016

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Organic Chemistry

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