Abstract
Thiazolobenzyne, which is a benzyne species fused with a thiazole ring, was efficiently generated via an iodine-magnesium exchange reaction of an ortho-iodoaryl triflate-type precursor using a trimethylsilylmethyl Grignard reagent as an activator. A wide range of arynophiles reacted efficiently with the thiazolobenzynes generated by this method to afford various multisubstituted benzothiazoles.
| Original language | English |
|---|---|
| Pages (from-to) | 11199-11202 |
| Number of pages | 4 |
| Journal | Chemical Communications |
| Volume | 52 |
| Issue number | 75 |
| DOIs | |
| Publication status | Published - Jan 1 2016 |
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All Science Journal Classification (ASJC) codes
- Catalysis
- Electronic, Optical and Magnetic Materials
- Ceramics and Composites
- Chemistry(all)
- Surfaces, Coatings and Films
- Metals and Alloys
- Materials Chemistry
Cite this
Thiazolobenzyne : A versatile intermediate for multisubstituted benzothiazoles. / Yoshida, Suguru; Yano, Takahisa; Nishiyama, Yoshitake; Misawa, Yoshihiro; Kondo, Masakazu; Matsushita, Takeshi; Igawa, Kazunobu; Tomooka, Katsuhiko; Hosoya, Takamitsu.
In: Chemical Communications, Vol. 52, No. 75, 01.01.2016, p. 11199-11202.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Thiazolobenzyne
T2 - A versatile intermediate for multisubstituted benzothiazoles
AU - Yoshida, Suguru
AU - Yano, Takahisa
AU - Nishiyama, Yoshitake
AU - Misawa, Yoshihiro
AU - Kondo, Masakazu
AU - Matsushita, Takeshi
AU - Igawa, Kazunobu
AU - Tomooka, Katsuhiko
AU - Hosoya, Takamitsu
PY - 2016/1/1
Y1 - 2016/1/1
N2 - Thiazolobenzyne, which is a benzyne species fused with a thiazole ring, was efficiently generated via an iodine-magnesium exchange reaction of an ortho-iodoaryl triflate-type precursor using a trimethylsilylmethyl Grignard reagent as an activator. A wide range of arynophiles reacted efficiently with the thiazolobenzynes generated by this method to afford various multisubstituted benzothiazoles.
AB - Thiazolobenzyne, which is a benzyne species fused with a thiazole ring, was efficiently generated via an iodine-magnesium exchange reaction of an ortho-iodoaryl triflate-type precursor using a trimethylsilylmethyl Grignard reagent as an activator. A wide range of arynophiles reacted efficiently with the thiazolobenzynes generated by this method to afford various multisubstituted benzothiazoles.
UR - http://www.scopus.com/inward/record.url?scp=84987923385&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84987923385&partnerID=8YFLogxK
U2 - 10.1039/c6cc05112j
DO - 10.1039/c6cc05112j
M3 - Article
AN - SCOPUS:84987923385
VL - 52
SP - 11199
EP - 11202
JO - Chemical Communications
JF - Chemical Communications
SN - 1359-7345
IS - 75
ER -