"Threading" of Β-sheet peptides via radical polymerization

Takeshi Mori, Shiro Yasutake, Hideki Inoue, Keiji Minagawa, Masami Tanaka, Takuro Niidome, Yoshiki Katayama

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)

Abstract

A nonamer peptide containing a diene group in the center of the sequence was synthesized. When the peptide forms an antiparallel β-sheet, the diene groups align ca. 5 Å apart on the β-sheet. The diene groups successfully photopolymerized without distorting the β-sheet structure. The obtained β-sheet showed high stability against acid denaturation and addition of 1,1,1,3,3,3-hexafluoroisopropanol.

Original languageEnglish
Pages (from-to)318-321
Number of pages4
JournalBiomacromolecules
Volume8
Issue number2
DOIs
Publication statusPublished - Feb 1 2007

All Science Journal Classification (ASJC) codes

  • Bioengineering
  • Biomaterials
  • Polymers and Plastics
  • Materials Chemistry

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