Three-Dimensional Architecture and Distribution of Collagen Components in the Goat Hypophysis

Shotaro Nishimura, Shoji Tabata, Yoshi Nori Nakamura, Kaoru Okano, Hisao Iwamoto

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

The three-dimensional architecture of collagen fibrils in the connective tissue framework and the distribution of collagen types in the goat hypophysis were studied by the cell maceration method in combination with scanning electron microscopy (SEM) and immunohistochemistry. The pars distalis of the adenohypophysis consisted of many cell clusters. SEM revealed that the wall of cell clusters appeared as various-sized flat bundles of collagen fibrils woven in a basket-like configuration. In the pars tuberalis, the aggregates of collagen fibrils were denser and bundles thicker compared to the pars distalis. The density of collagen fibrils changed from the pars tuberalis to pars distalis without a distinct border. The collagen framework in the pars intermedia was mainly divided into three parts, the dorsal region with large hollows, the middle region, and the ventral sheet facing the cavum hypophysis. In the lobus nervosus of the neurohypophysis, the collagen network exhibited a sponge-like appearance at low magnification. Collagen fibrils of various sizes consisted of loose wavy bundles distributed around the cavities. Immunohistochemistry revealed types I, III, IV, V, and VI collagen throughout the hypophysis. It is concluded that to maintain structural and functional integration, the components of collagen are in different configurations throughout the regions of the goat hypophysis.

Original languageEnglish
Pages (from-to)275-286
Number of pages12
JournalAnatomical Record - Part A Discoveries in Molecular, Cellular, and Evolutionary Biology
Volume277
Issue number2
DOIs
Publication statusPublished - Jan 1 2004

Fingerprint

pituitary gland
Pituitary Gland
Goats
collagen
Collagen
goats
Posterior Pituitary Gland
Electron Scanning Microscopy
immunohistochemistry
scanning electron microscopy
Immunohistochemistry
posterior pituitary
anterior pituitary
Anterior Pituitary Gland
maceration
Porifera
protein aggregates
Tissue Distribution
connective tissues
Connective Tissue

All Science Journal Classification (ASJC) codes

  • Anatomy
  • Agricultural and Biological Sciences (miscellaneous)

Cite this

Three-Dimensional Architecture and Distribution of Collagen Components in the Goat Hypophysis. / Nishimura, Shotaro; Tabata, Shoji; Nakamura, Yoshi Nori; Okano, Kaoru; Iwamoto, Hisao.

In: Anatomical Record - Part A Discoveries in Molecular, Cellular, and Evolutionary Biology, Vol. 277, No. 2, 01.01.2004, p. 275-286.

Research output: Contribution to journalArticle

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