Three-dimensional phase contrast magnetic resonance imaging validated to assess pulmonary artery flow in patients with chronic thromboembolic pulmonary hypertension

Masateru Kawakubo, Hiroshi Akamine, Yuzo Yamasaki, Atsushi Takemura, Kohtaro Abe, Kazuya Hosokawa, Junji Morishita, Michinobu Nagao

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

In this study, three-dimensional phase contrast magnetic resonance imaging (3D-PC MRI), a novel technique, was validated to assess pulmonary artery (PA) flow in patients with chronic thromboembolic pulmonary hypertension (CTEPH). The MR data of PAs from 3D-PC and two-dimensional PC (2D-PC) from before and after treatment for 3 patients with CTEPH were retrospectively analyzed. Additionally, 3D- and 2D-PC MR scans of PA were performed in 5 healthy volunteers. Correlation of stroke volumes (SVs) obtained by 3D-PC and 2D-PC was analyzed using Pearson’s correlation coefficients. There was an excellent correlation in the SV of main PA, left PA and right PA between 3D-PC and 2D-PC (main PA: r = 0.91, p < 0.01, left PA: r = 0.72, p < 0.01 and right PA: r = 0.77, p < 0.01). In conclusion, 3D-PC MRI was able to accurately quantify the PA flow in patients with CTEPH.

Original languageEnglish
Pages (from-to)249-255
Number of pages7
JournalRadiological physics and technology
Volume10
Issue number2
DOIs
Publication statusPublished - Jun 1 2017

Fingerprint

hypertension
phase contrast
arteries
Pulmonary Hypertension
Pulmonary Artery
magnetic resonance
Magnetic Resonance Imaging
stroke volume
Stroke Volume
correlation coefficients
Healthy Volunteers

All Science Journal Classification (ASJC) codes

  • Radiation
  • Physical Therapy, Sports Therapy and Rehabilitation
  • Radiology Nuclear Medicine and imaging

Cite this

@article{a44b5f0248b84ca0b3bc4eb13bae2124,
title = "Three-dimensional phase contrast magnetic resonance imaging validated to assess pulmonary artery flow in patients with chronic thromboembolic pulmonary hypertension",
abstract = "In this study, three-dimensional phase contrast magnetic resonance imaging (3D-PC MRI), a novel technique, was validated to assess pulmonary artery (PA) flow in patients with chronic thromboembolic pulmonary hypertension (CTEPH). The MR data of PAs from 3D-PC and two-dimensional PC (2D-PC) from before and after treatment for 3 patients with CTEPH were retrospectively analyzed. Additionally, 3D- and 2D-PC MR scans of PA were performed in 5 healthy volunteers. Correlation of stroke volumes (SVs) obtained by 3D-PC and 2D-PC was analyzed using Pearson’s correlation coefficients. There was an excellent correlation in the SV of main PA, left PA and right PA between 3D-PC and 2D-PC (main PA: r = 0.91, p < 0.01, left PA: r = 0.72, p < 0.01 and right PA: r = 0.77, p < 0.01). In conclusion, 3D-PC MRI was able to accurately quantify the PA flow in patients with CTEPH.",
author = "Masateru Kawakubo and Hiroshi Akamine and Yuzo Yamasaki and Atsushi Takemura and Kohtaro Abe and Kazuya Hosokawa and Junji Morishita and Michinobu Nagao",
year = "2017",
month = "6",
day = "1",
doi = "10.1007/s12194-016-0383-0",
language = "English",
volume = "10",
pages = "249--255",
journal = "Radiological Physics and Technology",
issn = "1865-0333",
publisher = "Springer Japan",
number = "2",

}

TY - JOUR

T1 - Three-dimensional phase contrast magnetic resonance imaging validated to assess pulmonary artery flow in patients with chronic thromboembolic pulmonary hypertension

AU - Kawakubo, Masateru

AU - Akamine, Hiroshi

AU - Yamasaki, Yuzo

AU - Takemura, Atsushi

AU - Abe, Kohtaro

AU - Hosokawa, Kazuya

AU - Morishita, Junji

AU - Nagao, Michinobu

PY - 2017/6/1

Y1 - 2017/6/1

N2 - In this study, three-dimensional phase contrast magnetic resonance imaging (3D-PC MRI), a novel technique, was validated to assess pulmonary artery (PA) flow in patients with chronic thromboembolic pulmonary hypertension (CTEPH). The MR data of PAs from 3D-PC and two-dimensional PC (2D-PC) from before and after treatment for 3 patients with CTEPH were retrospectively analyzed. Additionally, 3D- and 2D-PC MR scans of PA were performed in 5 healthy volunteers. Correlation of stroke volumes (SVs) obtained by 3D-PC and 2D-PC was analyzed using Pearson’s correlation coefficients. There was an excellent correlation in the SV of main PA, left PA and right PA between 3D-PC and 2D-PC (main PA: r = 0.91, p < 0.01, left PA: r = 0.72, p < 0.01 and right PA: r = 0.77, p < 0.01). In conclusion, 3D-PC MRI was able to accurately quantify the PA flow in patients with CTEPH.

AB - In this study, three-dimensional phase contrast magnetic resonance imaging (3D-PC MRI), a novel technique, was validated to assess pulmonary artery (PA) flow in patients with chronic thromboembolic pulmonary hypertension (CTEPH). The MR data of PAs from 3D-PC and two-dimensional PC (2D-PC) from before and after treatment for 3 patients with CTEPH were retrospectively analyzed. Additionally, 3D- and 2D-PC MR scans of PA were performed in 5 healthy volunteers. Correlation of stroke volumes (SVs) obtained by 3D-PC and 2D-PC was analyzed using Pearson’s correlation coefficients. There was an excellent correlation in the SV of main PA, left PA and right PA between 3D-PC and 2D-PC (main PA: r = 0.91, p < 0.01, left PA: r = 0.72, p < 0.01 and right PA: r = 0.77, p < 0.01). In conclusion, 3D-PC MRI was able to accurately quantify the PA flow in patients with CTEPH.

UR - http://www.scopus.com/inward/record.url?scp=84992343793&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84992343793&partnerID=8YFLogxK

U2 - 10.1007/s12194-016-0383-0

DO - 10.1007/s12194-016-0383-0

M3 - Article

C2 - 27783357

AN - SCOPUS:84992343793

VL - 10

SP - 249

EP - 255

JO - Radiological Physics and Technology

JF - Radiological Physics and Technology

SN - 1865-0333

IS - 2

ER -