Thymus Exclusivity: All the Right Conditions for T Cells

Hiromi Iwasaki, Koichi Akashi

Research output: Contribution to journalShort survey

1 Citation (Scopus)

Abstract

A fraction of primitive "lymphoid" precursors retain plasticity for myeloid differentiation. In this issue of Immunity, Laiosa et al. describe that Notch-Delta signals can protect thymic precursors from reprogramming into the myeloid lineage, antagonizing the enforced myeloid transcription factors such as PU.1 and C/EBPα.

Original languageEnglish
Pages (from-to)697-700
Number of pages4
JournalImmunity
Volume25
Issue number5
DOIs
Publication statusPublished - Nov 2006

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Immunology
  • Infectious Diseases

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