Total synthesis of (+)-bongkrekic acid

Mitsuru Shindo, Tomoyuki Sugioka, Yuko Umaba, Kozo Shishido

Research output: Contribution to journalArticlepeer-review

18 Citations (Scopus)

Abstract

Total synthesis of bongkrekic acid, an important apoptosis inhibitor, has been accomplished. The strategy includes inexpensive starting materials, asymmetric alkylation, anionic allyl coupling and oxidative manipulations. This process would provide a sufficient amount of bongkrekic acid and its analogues.

Original languageEnglish
Pages (from-to)8863-8866
Number of pages4
JournalTetrahedron Letters
Volume45
Issue number48
DOIs
Publication statusPublished - Nov 22 2004
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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