Total synthesis of bongkrekic acid via sequential suzuki-miyaura coupling reactions

Makoto Kanematsu, Mitsuru Shindo, Masahiro Yoshida, Kozo Shishido

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

An efficient total synthesis of (+)-bongkrekic acid, a potent apoptosis inhibitor, has been accomplished by employing a convergent strategy based on the Suzuki-Miyaura coupling of three fully functionalized segments.

Original languageEnglish
Pages (from-to)2893-2904
Number of pages12
JournalSynthesis
Issue number17
DOIs
Publication statusPublished - Nov 18 2009

Fingerprint

Bongkrekic Acid
Cell death
Apoptosis
Acids

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Organic Chemistry

Cite this

Total synthesis of bongkrekic acid via sequential suzuki-miyaura coupling reactions. / Kanematsu, Makoto; Shindo, Mitsuru; Yoshida, Masahiro; Shishido, Kozo.

In: Synthesis, No. 17, 18.11.2009, p. 2893-2904.

Research output: Contribution to journalArticle

Kanematsu, Makoto ; Shindo, Mitsuru ; Yoshida, Masahiro ; Shishido, Kozo. / Total synthesis of bongkrekic acid via sequential suzuki-miyaura coupling reactions. In: Synthesis. 2009 ; No. 17. pp. 2893-2904.
@article{132ac3bec315468fb7241a4c56d889ad,
title = "Total synthesis of bongkrekic acid via sequential suzuki-miyaura coupling reactions",
abstract = "An efficient total synthesis of (+)-bongkrekic acid, a potent apoptosis inhibitor, has been accomplished by employing a convergent strategy based on the Suzuki-Miyaura coupling of three fully functionalized segments.",
author = "Makoto Kanematsu and Mitsuru Shindo and Masahiro Yoshida and Kozo Shishido",
year = "2009",
month = "11",
day = "18",
doi = "10.1055/s-0029-1216928",
language = "English",
pages = "2893--2904",
journal = "Synthesis",
issn = "0039-7881",
publisher = "Georg Thieme Verlag",
number = "17",

}

TY - JOUR

T1 - Total synthesis of bongkrekic acid via sequential suzuki-miyaura coupling reactions

AU - Kanematsu, Makoto

AU - Shindo, Mitsuru

AU - Yoshida, Masahiro

AU - Shishido, Kozo

PY - 2009/11/18

Y1 - 2009/11/18

N2 - An efficient total synthesis of (+)-bongkrekic acid, a potent apoptosis inhibitor, has been accomplished by employing a convergent strategy based on the Suzuki-Miyaura coupling of three fully functionalized segments.

AB - An efficient total synthesis of (+)-bongkrekic acid, a potent apoptosis inhibitor, has been accomplished by employing a convergent strategy based on the Suzuki-Miyaura coupling of three fully functionalized segments.

UR - http://www.scopus.com/inward/record.url?scp=70449440678&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=70449440678&partnerID=8YFLogxK

U2 - 10.1055/s-0029-1216928

DO - 10.1055/s-0029-1216928

M3 - Article

AN - SCOPUS:70449440678

SP - 2893

EP - 2904

JO - Synthesis

JF - Synthesis

SN - 0039-7881

IS - 17

ER -