Total synthesis of tetronolide, the aglycon of tetrocarcins

Kei Takeda, Eiji Kawanishi, Hitoshi Nakamura, Eiichi Yoshii

Research output: Contribution to journalArticlepeer-review

58 Citations (Scopus)

Abstract

The first total synthesis of tetronolide (1) has been achieved via coupling of spirotetronate 3 with octahydronaphthalene aldehyde 17 and subsequent macrocyclization of ω-sulfone-α-aldehyde 2, leading to confirmation of the absolute configuration of 1.

Original languageEnglish
Pages (from-to)4925-4928
Number of pages4
JournalTetrahedron Letters
Volume32
Issue number37
DOIs
Publication statusPublished - Sep 9 1991
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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