Total synthesis of tetronolide, the aglycon of tetrocarcins

Kei Takeda; Eiji Kawanishi; Hitoshi Nakamura; Eiichi Yoshii

doi:10.1016/S0040-4039(00)93498-1

Total synthesis of tetronolide, the aglycon of tetrocarcins

Kei Takeda, Eiji Kawanishi, Hitoshi Nakamura, Eiichi Yoshii

Research output: Contribution to journal › Article › peer-review

23 Citations (Scopus)

Abstract

The first total synthesis of tetronolide (1) has been achieved via coupling of spirotetronate 3 with octahydronaphthalene aldehyde 17 and subsequent macrocyclization of ω-sulfone-α-aldehyde 2, leading to confirmation of the absolute configuration of 1.

Original language	English
Pages (from-to)	4925-4928
Number of pages	4
Journal	Tetrahedron Letters
Volume	32
Issue number	37
DOIs	https://doi.org/10.1016/S0040-4039(00)93498-1
Publication status	Published - Sept 9 1991
Externally published	Yes

All Science Journal Classification (ASJC) codes

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/S0040-4039(00)93498-1

Cite this

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title = "Total synthesis of tetronolide, the aglycon of tetrocarcins",

abstract = "The first total synthesis of tetronolide (1) has been achieved via coupling of spirotetronate 3 with octahydronaphthalene aldehyde 17 and subsequent macrocyclization of ω-sulfone-α-aldehyde 2, leading to confirmation of the absolute configuration of 1.",

author = "Kei Takeda and Eiji Kawanishi and Hitoshi Nakamura and Eiichi Yoshii",

year = "1991",

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AU - Takeda, Kei

AU - Kawanishi, Eiji

AU - Nakamura, Hitoshi

AU - Yoshii, Eiichi

PY - 1991/9/9

Y1 - 1991/9/9

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AB - The first total synthesis of tetronolide (1) has been achieved via coupling of spirotetronate 3 with octahydronaphthalene aldehyde 17 and subsequent macrocyclization of ω-sulfone-α-aldehyde 2, leading to confirmation of the absolute configuration of 1.

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M3 - Article

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JO - Tetrahedron Letters

JF - Tetrahedron Letters

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ER -

Total synthesis of tetronolide, the aglycon of tetrocarcins

Abstract

All Science Journal Classification (ASJC) codes

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