Transcriptome profiling of Musculus longissimus dorsi in two cattle breeds with different intramuscular fat deposition

Elke Albrecht, Katrin Komolka, Siriluck Ponsuksili, Takafumi Gotoh, Klaus Wimmers, Steffen Maak

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Intramuscular fat (IMF) deposition is a physiological process in cattle and is highly variable among breeds suggesting a large influence of genetic factors besides environmental factors. In order to elucidate molecular pathways underlying the genetic variation in this trait we compared transcriptomes of Musculus longissimus dorsi (MLD) in steers of Japanese Black and Holstein Friesian cattle breeds fed a high energy diet typically applied in Japan to achieve maximum IMF content. We identified a total of 569 differentially expressed genes (DEGs) with the majority (433) up-regulated in Japanese Black cattle. This breed is characterized by an extreme capacity for IMF deposition. Subsequent Ingenuity Pathway Analysis (IPA) revealed a gene network linking parameters of cell morphology and maintenance with lipid metabolism. The data from this study were deposited in NCBI's Gene Expression Omnibus and are accessible through GEO Series accession number GSE75348. We provide here a dataset which is of potential value to dissect molecular pathways influencing differences in fat deposition under high-energy nutrition.

Original languageEnglish
Pages (from-to)109-111
Number of pages3
JournalGenomics Data
Volume7
DOIs
Publication statusPublished - Mar 1 2016

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Gene Expression Profiling
Fats
Nutrition
Genes
Physiological Phenomena
Gene Regulatory Networks
Transcriptome
Lipid Metabolism
Gene expression
Japan
Maintenance
Diet
Gene Expression

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Biochemistry
  • Molecular Medicine
  • Genetics

Cite this

Transcriptome profiling of Musculus longissimus dorsi in two cattle breeds with different intramuscular fat deposition. / Albrecht, Elke; Komolka, Katrin; Ponsuksili, Siriluck; Gotoh, Takafumi; Wimmers, Klaus; Maak, Steffen.

In: Genomics Data, Vol. 7, 01.03.2016, p. 109-111.

Research output: Contribution to journalArticle

Albrecht, Elke ; Komolka, Katrin ; Ponsuksili, Siriluck ; Gotoh, Takafumi ; Wimmers, Klaus ; Maak, Steffen. / Transcriptome profiling of Musculus longissimus dorsi in two cattle breeds with different intramuscular fat deposition. In: Genomics Data. 2016 ; Vol. 7. pp. 109-111.
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AU - Maak, Steffen

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