Transcutaneous immunization by a solid-in-oil nanodispersion

Yoshiro Tahara; Kenichi Namatsu; Noriho Kamiya; Masayori Hagimori; Seitaro Kamiya; Masayuki Arakawa; Masahiro Goto

doi:10.1039/c0cc03600e

Transcutaneous immunization by a solid-in-oil nanodispersion

Yoshiro Tahara, Kenichi Namatsu, Noriho Kamiya, Masayori Hagimori, Seitaro Kamiya, Masayuki Arakawa, Masahiro Goto

Applied Chemistry

Research output: Contribution to journal › Article › peer-review

31 Citations (Scopus)

Abstract

We have successfully achieved transcutaneous immunization without the use of any skin pre-treatment or immune-stimulant adjuvant by applying a solid-in-oil (S/O) nanodispersion: an oil-based nanodispersion of antigens coated with hydrophobic surfactant molecules. This finding indicates that the S/O nanodispersion has great promise for effective transcutaneous vaccination.

Original language	English
Pages (from-to)	9200-9202
Number of pages	3
Journal	Chemical Communications
Volume	46
Issue number	48
DOIs	https://doi.org/10.1039/c0cc03600e
Publication status	Published - Dec 28 2010

All Science Journal Classification (ASJC) codes

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
Chemistry(all)
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1039/c0cc03600e

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AU - Tahara, Yoshiro

AU - Namatsu, Kenichi

AU - Kamiya, Noriho

AU - Hagimori, Masayori

AU - Kamiya, Seitaro

AU - Arakawa, Masayuki

AU - Goto, Masahiro

PY - 2010/12/28

Y1 - 2010/12/28

N2 - We have successfully achieved transcutaneous immunization without the use of any skin pre-treatment or immune-stimulant adjuvant by applying a solid-in-oil (S/O) nanodispersion: an oil-based nanodispersion of antigens coated with hydrophobic surfactant molecules. This finding indicates that the S/O nanodispersion has great promise for effective transcutaneous vaccination.

AB - We have successfully achieved transcutaneous immunization without the use of any skin pre-treatment or immune-stimulant adjuvant by applying a solid-in-oil (S/O) nanodispersion: an oil-based nanodispersion of antigens coated with hydrophobic surfactant molecules. This finding indicates that the S/O nanodispersion has great promise for effective transcutaneous vaccination.

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Transcutaneous immunization by a solid-in-oil nanodispersion

Abstract

All Science Journal Classification (ASJC) codes

UN SDGs

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