Transcutaneous immunization by a solid-in-oil nanodispersion

Yoshiro Tahara, Kenichi Namatsu, Noriho Kamiya, Masayori Hagimori, Seitaro Kamiya, Masayuki Arakawa, Masahiro Goto

Research output: Contribution to journalArticlepeer-review

28 Citations (Scopus)

Abstract

We have successfully achieved transcutaneous immunization without the use of any skin pre-treatment or immune-stimulant adjuvant by applying a solid-in-oil (S/O) nanodispersion: an oil-based nanodispersion of antigens coated with hydrophobic surfactant molecules. This finding indicates that the S/O nanodispersion has great promise for effective transcutaneous vaccination.

Original languageEnglish
Pages (from-to)9200-9202
Number of pages3
JournalChemical Communications
Volume46
Issue number48
DOIs
Publication statusPublished - Dec 28 2010

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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