Transdermal delivery of insulin using a solid-in-oil nanodispersion enhanced by arginine-rich peptides

Yoshiro Tahara, Shota Honda, Noriho Kamiya, Masahiro Goto

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

A solid-in-oil nanodispersion that utilizes an oil-based vehicle of proteins was developed as a unique protein-delivery system into the skin. We enhanced the permeability of insulin and accomplished transdermal delivery of insulin by the collaborative effects of a S/O nanodispersion and arginine-rich peptides.

Original languageEnglish
Pages (from-to)1496-1499
Number of pages4
JournalMedChemComm
Volume3
Issue number12
DOIs
Publication statusPublished - Dec 1 2012

Fingerprint

Arginine
Oils
Insulin
Peptides
Permeability
Skin
Proteins

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Organic Chemistry

Cite this

Transdermal delivery of insulin using a solid-in-oil nanodispersion enhanced by arginine-rich peptides. / Tahara, Yoshiro; Honda, Shota; Kamiya, Noriho; Goto, Masahiro.

In: MedChemComm, Vol. 3, No. 12, 01.12.2012, p. 1496-1499.

Research output: Contribution to journalArticle

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