Transformation of α-substituted propanols into γ-amino alcohols through nickel-catalyzed amination on the terminal γ-carbon of propanols

Satoshi Ueno, Kazumi Usui, Ryoichi Kuwano

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

A nickel-phosphine complex was found to be effective as the catalyst for the transformation of alcohols into β-enaminones, which was successively converted into γ-amino alcohols by a conventional reductant. The sequential transformation is equivalent to the carbon-nitrogen bond formation at the γ-position of saturated alcohols.

Original languageEnglish
Pages (from-to)1303-1307
Number of pages5
JournalSynlett
Issue number9
DOIs
Publication statusPublished - May 30 2011

All Science Journal Classification (ASJC) codes

  • Organic Chemistry

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