Transformation of α-substituted propanols into γ-amino alcohols through nickel-catalyzed amination on the terminal γ-carbon of propanols

Satoshi Ueno, Kazumi Usui, Ryoichi Kuwano

Research output: Contribution to journal › Article

8 Citations (Scopus)

Abstract

A nickel-phosphine complex was found to be effective as the catalyst for the transformation of alcohols into β-enaminones, which was successively converted into γ-amino alcohols by a conventional reductant. The sequential transformation is equivalent to the carbon-nitrogen bond formation at the γ-position of saturated alcohols.

Original languageEnglish
Pages (from-to)1303-1307
Number of pages5
JournalSynlett
Issue number9
DOIs
Publication statusPublished - May 30 2011

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Propanols
Amino Alcohols
Amination
phosphine
Nickel
Carbon
Alcohols
Reducing Agents
Nitrogen
Catalysts

All Science Journal Classification (ASJC) codes

  • Organic Chemistry

Cite this

Transformation of α-substituted propanols into γ-amino alcohols through nickel-catalyzed amination on the terminal γ-carbon of propanols. / Ueno, Satoshi; Usui, Kazumi; Kuwano, Ryoichi.

In: Synlett, No. 9, 30.05.2011, p. 1303-1307.

Research output: Contribution to journal › Article

Ueno, S, Usui, K & Kuwano, R 2011, 'Transformation of α-substituted propanols into γ-amino alcohols through nickel-catalyzed amination on the terminal γ-carbon of propanols', Synlett, no. 9, pp. 1303-1307. https://doi.org/10.1055/s-0030-1260536
Ueno S, Usui K, Kuwano R. Transformation of α-substituted propanols into γ-amino alcohols through nickel-catalyzed amination on the terminal γ-carbon of propanols. Synlett. 2011 May 30;(9):1303-1307. https://doi.org/10.1055/s-0030-1260536
Ueno, Satoshi ; Usui, Kazumi ; Kuwano, Ryoichi. / Transformation of α-substituted propanols into γ-amino alcohols through nickel-catalyzed amination on the terminal γ-carbon of propanols. In: Synlett. 2011 ; No. 9. pp. 1303-1307.
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