Transformation of α-substituted propanols into γ-amino alcohols through nickel-catalyzed amination on the terminal γ-carbon of propanols

Satoshi Ueno, Kazumi Usui, Ryoichi Kuwano

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

A nickel-phosphine complex was found to be effective as the catalyst for the transformation of alcohols into β-enaminones, which was successively converted into γ-amino alcohols by a conventional reductant. The sequential transformation is equivalent to the carbon-nitrogen bond formation at the γ-position of saturated alcohols.

Original languageEnglish
Pages (from-to)1303-1307
Number of pages5
JournalSynlett
Issue number9
DOIs
Publication statusPublished - May 30 2011

Fingerprint

Propanols
Amino Alcohols
Amination
phosphine
Nickel
Carbon
Alcohols
Reducing Agents
Nitrogen
Catalysts

All Science Journal Classification (ASJC) codes

  • Organic Chemistry

Cite this

Transformation of α-substituted propanols into γ-amino alcohols through nickel-catalyzed amination on the terminal γ-carbon of propanols. / Ueno, Satoshi; Usui, Kazumi; Kuwano, Ryoichi.

In: Synlett, No. 9, 30.05.2011, p. 1303-1307.

Research output: Contribution to journalArticle

@article{4a15b25ee3424c0f8e1c27dbf0f44af7,
title = "Transformation of α-substituted propanols into γ-amino alcohols through nickel-catalyzed amination on the terminal γ-carbon of propanols",
abstract = "A nickel-phosphine complex was found to be effective as the catalyst for the transformation of alcohols into β-enaminones, which was successively converted into γ-amino alcohols by a conventional reductant. The sequential transformation is equivalent to the carbon-nitrogen bond formation at the γ-position of saturated alcohols.",
author = "Satoshi Ueno and Kazumi Usui and Ryoichi Kuwano",
year = "2011",
month = "5",
day = "30",
doi = "10.1055/s-0030-1260536",
language = "English",
pages = "1303--1307",
journal = "Synlett",
issn = "0936-5214",
publisher = "Georg Thieme Verlag",
number = "9",

}

TY - JOUR

T1 - Transformation of α-substituted propanols into γ-amino alcohols through nickel-catalyzed amination on the terminal γ-carbon of propanols

AU - Ueno, Satoshi

AU - Usui, Kazumi

AU - Kuwano, Ryoichi

PY - 2011/5/30

Y1 - 2011/5/30

N2 - A nickel-phosphine complex was found to be effective as the catalyst for the transformation of alcohols into β-enaminones, which was successively converted into γ-amino alcohols by a conventional reductant. The sequential transformation is equivalent to the carbon-nitrogen bond formation at the γ-position of saturated alcohols.

AB - A nickel-phosphine complex was found to be effective as the catalyst for the transformation of alcohols into β-enaminones, which was successively converted into γ-amino alcohols by a conventional reductant. The sequential transformation is equivalent to the carbon-nitrogen bond formation at the γ-position of saturated alcohols.

UR - http://www.scopus.com/inward/record.url?scp=79957534459&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79957534459&partnerID=8YFLogxK

U2 - 10.1055/s-0030-1260536

DO - 10.1055/s-0030-1260536

M3 - Article

SP - 1303

EP - 1307

JO - Synlett

JF - Synlett

SN - 0936-5214

IS - 9

ER -