Transformation of carbonates into sulfones at the benzylic position via palladium-catalyzed benzylic substitution

Ryoichi Kuwano, Yutaka Kondo, Tsuyoshi Shirahama

Research output: Contribution to journalArticle

53 Citations (Scopus)

Abstract

(Chemical Equation Presented) The nucleophilic substitution of benzylic carbonates with sodium arenesulfinates was catalyzed by the palladium complex generated in situ from [Pd(η3-C3H5)Cl] 2 and DPEphos [bis(2-diphenylphosphinophenyl)ether]. The catalytic reaction proceeded in DMSO at 80°C and gave a variety of benzylic sulfones in high yields.

Original languageEnglish
Pages (from-to)2973-2975
Number of pages3
JournalOrganic Letters
Volume7
Issue number14
DOIs
Publication statusPublished - Jul 7 2005

Fingerprint

Sulfones
sulfones
Carbonates
Palladium
Dimethyl Sulfoxide
Ether
palladium
ethers
carbonates
Substitution reactions
Sodium
sodium
substitutes
sodium carbonate

All Science Journal Classification (ASJC) codes

  • Molecular Medicine

Cite this

Transformation of carbonates into sulfones at the benzylic position via palladium-catalyzed benzylic substitution. / Kuwano, Ryoichi; Kondo, Yutaka; Shirahama, Tsuyoshi.

In: Organic Letters, Vol. 7, No. 14, 07.07.2005, p. 2973-2975.

Research output: Contribution to journalArticle

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