Transient antiphospholipid syndrome associated with primary cytomegalovirus infection: a case report and literature review

Tsuyoshi Nakayama, Mitsuteru Akahoshi, Kensuke Irino, Yasutaka Kimoto, Yojiro Arinobu, Hiroaki Niiro, Hiroshi Tsukamoto, Takahiko Horiuchi, Koichi Akashi

Research output: Contribution to journalArticle

Abstract

Viral infection is known to induce transient autoimmunity in humans. Acute cytomegalovirus (CMV) infection is implicated in occasional thrombosis formation. We here, for the first time, report a 19-year-old female who had an acute CMV infection, leading to a deep venous thrombosis and a pulmonary embolism along with transient appearance of lupus anticoagulant. The pathological role of antiphospholipid antibodies in CMV-mediated thrombosis is discussed.

Original languageEnglish
Pages (from-to)271548
JournalCase reports in rheumatology
Volume2014
DOIs
Publication statusPublished - 2014

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