Transition of mechanical property of porous alginate scaffold with cells during culture period

Shinji Sakai, Hiroki Masuhara, Yusuke Yamada, Tsutomu Ono, Hiroyuki Ijima, Koei Kawakami

Research output: Contribution to journalArticle

18 Citations (Scopus)


The rupture forces of porous alginate scaffolds seeded with hepatocytes or fibroblast-like cells increased during 3 d of culture and then decreased. The phenomenon was independent of the number of viable cells within the scaffolds, but dependent on protein adsorption to the alginate as well as a reduction in the degree of crosslinks of the calcium-alginate gel.

Original languageEnglish
Pages (from-to)127-129
Number of pages3
JournalJournal of Bioscience and Bioengineering
Issue number1
Publication statusPublished - Jan 1 2005


All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Bioengineering
  • Applied Microbiology and Biotechnology

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