Transition of mechanical property of porous alginate scaffold with cells during culture period

Shinji Sakai, Hiroki Masuhara, Yusuke Yamada, Tsutomu Ono, Hiroyuki Ijima, Koei Kawakami

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

The rupture forces of porous alginate scaffolds seeded with hepatocytes or fibroblast-like cells increased during 3 d of culture and then decreased. The phenomenon was independent of the number of viable cells within the scaffolds, but dependent on protein adsorption to the alginate as well as a reduction in the degree of crosslinks of the calcium-alginate gel.

Original languageEnglish
Pages (from-to)127-129
Number of pages3
JournalJournal of Bioscience and Bioengineering
Volume100
Issue number1
DOIs
Publication statusPublished - Jan 1 2005

Fingerprint

Alginate
Scaffolds (biology)
Cell culture
Cell Culture Techniques
Scaffolds
Mechanical properties
Fibroblasts
Adsorption
Rupture
Hepatocytes
Calcium
Gels
Cell Count
Proteins
alginic acid

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Bioengineering
  • Applied Microbiology and Biotechnology

Cite this

Transition of mechanical property of porous alginate scaffold with cells during culture period. / Sakai, Shinji; Masuhara, Hiroki; Yamada, Yusuke; Ono, Tsutomu; Ijima, Hiroyuki; Kawakami, Koei.

In: Journal of Bioscience and Bioengineering, Vol. 100, No. 1, 01.01.2005, p. 127-129.

Research output: Contribution to journalArticle

Sakai, Shinji ; Masuhara, Hiroki ; Yamada, Yusuke ; Ono, Tsutomu ; Ijima, Hiroyuki ; Kawakami, Koei. / Transition of mechanical property of porous alginate scaffold with cells during culture period. In: Journal of Bioscience and Bioengineering. 2005 ; Vol. 100, No. 1. pp. 127-129.
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