Transplantation of neural stem cells with valproate for spinal cord injury

Masahiko Abematsu, Kinichi Nakashima

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

Abstract

The regenerative capacity of an injured spinal cord is limited, and once paralysis occurs, it is difficult to improve the situation. We have developed a treatment method called the HINT method (HDAC Inhibitor and Neural stem cell Transplantation) that improves hind limb motor functionality in mice with severe spinal cord injuries by using a combination of antiepileptic drugs and neural stem cells. This chapter will introduce you to the new neural damage reconstruction mechanism employed in the HINT method.

Original languageEnglish
Title of host publicationNeuroprotection and Regeneration of the Spinal Cord
PublisherSpringer Japan
Pages247-253
Number of pages7
Volume9784431545026
ISBN (Electronic)9784431545026
ISBN (Print)4431545018, 9784431545019
DOIs
Publication statusPublished - Nov 1 2014

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Neural Stem Cells
Valproic Acid
Spinal Cord Injuries
Transplantation
Histone Deacetylase Inhibitors
Stem Cell Transplantation
Paralysis
Anticonvulsants
Spinal Cord
Extremities
Therapeutics

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Abematsu, M., & Nakashima, K. (2014). Transplantation of neural stem cells with valproate for spinal cord injury. In Neuroprotection and Regeneration of the Spinal Cord (Vol. 9784431545026, pp. 247-253). Springer Japan. https://doi.org/10.1007/978-4-431-54502-6_20

Transplantation of neural stem cells with valproate for spinal cord injury. / Abematsu, Masahiko; Nakashima, Kinichi.

Neuroprotection and Regeneration of the Spinal Cord. Vol. 9784431545026 Springer Japan, 2014. p. 247-253.

Research output: Chapter in Book/Report/Conference proceedingChapter

Abematsu, M & Nakashima, K 2014, Transplantation of neural stem cells with valproate for spinal cord injury. in Neuroprotection and Regeneration of the Spinal Cord. vol. 9784431545026, Springer Japan, pp. 247-253. https://doi.org/10.1007/978-4-431-54502-6_20
Abematsu M, Nakashima K. Transplantation of neural stem cells with valproate for spinal cord injury. In Neuroprotection and Regeneration of the Spinal Cord. Vol. 9784431545026. Springer Japan. 2014. p. 247-253 https://doi.org/10.1007/978-4-431-54502-6_20
Abematsu, Masahiko ; Nakashima, Kinichi. / Transplantation of neural stem cells with valproate for spinal cord injury. Neuroprotection and Regeneration of the Spinal Cord. Vol. 9784431545026 Springer Japan, 2014. pp. 247-253
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