The regenerative capacity of an injured spinal cord is limited, and once paralysis occurs, it is difficult to improve the situation. We have developed a treatment method called the HINT method (HDAC Inhibitor and Neural stem cell Transplantation) that improves hind limb motor functionality in mice with severe spinal cord injuries by using a combination of antiepileptic drugs and neural stem cells. This chapter will introduce you to the new neural damage reconstruction mechanism employed in the HINT method.
|Title of host publication||Neuroprotection and Regeneration of the Spinal Cord|
|Number of pages||7|
|ISBN (Print)||4431545018, 9784431545019|
|Publication status||Published - Nov 1 2014|
All Science Journal Classification (ASJC) codes