Trapping and identifying single-nanoparticles using a low-aspect-ratio nanopore

Makusu Tsutsui, Yoichi Maeda, Yuhui He, Sadato Hongo, Sou Ryuzaki, Satoyuki Kawano, Tomoji Kawai, Masateru Taniguchi

Research output: Contribution to journalArticlepeer-review

29 Citations (Scopus)


Manipulation of particles and molecules in fluid is a fundamental technology in biosensors. Here, we report electrical trapping and identification of single-nanoparticles using a low-aspect-ratio nanopore. Particle trapping and detrapping are implemented through a control of the cross-membrane electrophoretic voltage. This electrical method is found to enable placing an individual nanoparticle in vicinity of a lithographically-defined nanopore by virtue of the balance between the two counteracting factors, electrostatic and electroosmotic forces. We also demonstrate identification of trapped nanoparticles by the ionic current through the particle-pore gap space. This technique may find applications in electrode-embedded nanopore sensors.

Original languageEnglish
Article number013108
JournalApplied Physics Letters
Issue number1
Publication statusPublished - Jul 1 2013
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Physics and Astronomy (miscellaneous)


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