Traumatic medial temporal lobe epilepsy associated with a subcortical lesion in the internal capsule - A case report

Nobutaka Mukae, Takato Morioka, Tetsuro Sayama, Takeshi Hamamura, Kosuke Makihara, Hiroshi Shigeto, Tomio Sasaki

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Abstract

Although there is no universally accepted definition, traumatic medial temporal lobe epilepsy (traumatic MTLE) can be generally defined as a type of post-traumatic epilepsy with medial temporal epileptogenicity. Previous studies have demonstrated that patients with traumatic MTLE frequently have hippocampal sclerosis (HS) coexisting with traumatic neocortical lesions. We report a 39-year-old MTLE patient with a subcortical lesion in the.internal capsule, suspected to be caused by mild diffuse axonal injury. The results of presurgical examinations and intraoperative electrocorticograms were consistent with a diagnosis of MTLE. Therefore, an anterior temporal lobectomy with hippocampectomy was performed. A 3D short tau inversion recovery 3-Tesla MRI scan clearly depicted possibly Wallerian degeneration in the temporal stem, which was continuous with the subcortical lesion. We speculate that Wallerian degeneration in the temporal stem could potentially involve the hippocampus, eventually leading to HS.

Original languageEnglish
Pages (from-to)1-9
Number of pages9
JournalEpilepsy and Seizure
Volume6
Issue number1
DOIs
Publication statusPublished - 2013

All Science Journal Classification (ASJC) codes

  • Clinical Neurology

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