Treating nonulcer dyspepsia considering both functional disorders of the digestive system and psychiatric conditions

Kazunori Mine, Fumitaka Kanazawa, Masako Hosoi, Naoko Kinukawa, Chiharu Kubo

Research output: Contribution to journalArticlepeer-review

23 Citations (Scopus)

Abstract

Nonulcer dyspepsia (NUD) is a common syndrome, but the optimal treatments have yet to be established. This study was performed to determine the most effective treatment for NUD. Subjects were recruited through the Department of General Internal Medicine at the Kyushu University Hospital because of their somatic symptoms. When no organic lesions were found, the patients were directed to consult our department (Psychosomatic Medicine); 194 consecutive NUD patients were studied. All subjects were assessed psychiatrically with the Structured Clinical Interview for DSM-III-R(SCID). Patients with serious NUD were hospitalized, and randomly divided into control (N = 42) and experimental groups (N = 86). The controls were treated with physical treatment alone. The experimental group received psychiatric treatment in addition, based on the results of SCID. The experimental group showed a significant improvement compared with the controls (P < 0.0001). The treatment for NUD taking into consideration both the physical and psychiatric conditions is highly effective.

Original languageEnglish
Pages (from-to)1241-1247
Number of pages7
JournalDigestive Diseases and Sciences
Volume43
Issue number6
DOIs
Publication statusPublished - Jun 25 1998

All Science Journal Classification (ASJC) codes

  • Physiology
  • Gastroenterology

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