Treatment results of two-stage operation for the patients with esophageal cancer concomitant with liver dysfunction

Mitsuhiro Yasuda, Hiroshi Saeki, Yuichiro Nakashima, Takafumi Yukaya, Satoshi Tsutsumi, Hirotada Tajiri, Yoko Zaitsu, Yasuo Tsuda, Yuta Kasagi, Koji Ando, Yu Imamura, Kippei Ohgaki, Tomohiko Akahoshi, Eiji Oki, Yoshihiko Maehara

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

Purpose: The aim of this study was to clarify the usefulness of two-stage operation for the patients with esophageal cancer who have liver dysfunction. Methods: Eight patients with esophageal cancer concomitant with liver dysfunction who underwent two-stage operation were analyzed. The patients initially underwent an esophagectomy, a cervical esophagostomy and a tube jejunostomy, and reconstruction with gastric tube was performed after the recovery of patients' condition. Results: The average time of the 1st and 2nd stage operation was 410.0 min and 438.9 min, respectively. The average amount of blood loss in the 1st and 2nd stage operation was 433.5 ml and 1556.8 ml, respectively. The average duration between the operations was 29.8 days. The antesternal route was selected for 5 patients (62.5%) and the retrosternal route was for 3 patients (37.5%). In the 1st stage operation, no postoperative complications were observed, while, complications developed in 5 (62.5%) patients, including 4 anastomotic leakages, after the 2nd stage operation. Pneumonia was not observed through two-stage operation. No in-hospital death was experienced. Conclusion: A two-stage operation might prevent the occurrence of critical postoperative complications for the patients with esophageal cancer concomitant with liver dysfunction.

Original languageEnglish
Pages (from-to)149-153
Number of pages5
JournalJournal of Medical Investigation
Volume62
Issue number3
DOIs
Publication statusPublished - Sep 18 2015

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)

Fingerprint Dive into the research topics of 'Treatment results of two-stage operation for the patients with esophageal cancer concomitant with liver dysfunction'. Together they form a unique fingerprint.

Cite this