Treatment results of two-stage operation for the patients with esophageal cancer concomitant with liver dysfunction

Mitsuhiro Yasuda, Hiroshi Saeki, Yuichiro Nakashima, Takafumi Yukaya, Satoshi Tsutsumi, Hirotada Tajiri, Yoko Zaitsu, Yasuo Tsuda, Yuta Kasagi, Koji Ando, Yu Imamura, Kippei Ohgaki, Tomohiko Akahoshi, Eiji Oki, Yoshihiko Maehara

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Purpose: The aim of this study was to clarify the usefulness of two-stage operation for the patients with esophageal cancer who have liver dysfunction. Methods: Eight patients with esophageal cancer concomitant with liver dysfunction who underwent two-stage operation were analyzed. The patients initially underwent an esophagectomy, a cervical esophagostomy and a tube jejunostomy, and reconstruction with gastric tube was performed after the recovery of patients' condition. Results: The average time of the 1st and 2nd stage operation was 410.0 min and 438.9 min, respectively. The average amount of blood loss in the 1st and 2nd stage operation was 433.5 ml and 1556.8 ml, respectively. The average duration between the operations was 29.8 days. The antesternal route was selected for 5 patients (62.5%) and the retrosternal route was for 3 patients (37.5%). In the 1st stage operation, no postoperative complications were observed, while, complications developed in 5 (62.5%) patients, including 4 anastomotic leakages, after the 2nd stage operation. Pneumonia was not observed through two-stage operation. No in-hospital death was experienced. Conclusion: A two-stage operation might prevent the occurrence of critical postoperative complications for the patients with esophageal cancer concomitant with liver dysfunction.

Original languageEnglish
Pages (from-to)149-153
Number of pages5
JournalJournal of Medical Investigation
Volume62
Issue number3
DOIs
Publication statusPublished - Sep 18 2015

Fingerprint

Esophageal Neoplasms
Liver
Liver Diseases
Blood
Therapeutics
Recovery
Esophagostomy
Jejunostomy
Anastomotic Leak
Esophagectomy
Pneumonia
Stomach

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Treatment results of two-stage operation for the patients with esophageal cancer concomitant with liver dysfunction. / Yasuda, Mitsuhiro; Saeki, Hiroshi; Nakashima, Yuichiro; Yukaya, Takafumi; Tsutsumi, Satoshi; Tajiri, Hirotada; Zaitsu, Yoko; Tsuda, Yasuo; Kasagi, Yuta; Ando, Koji; Imamura, Yu; Ohgaki, Kippei; Akahoshi, Tomohiko; Oki, Eiji; Maehara, Yoshihiko.

In: Journal of Medical Investigation, Vol. 62, No. 3, 18.09.2015, p. 149-153.

Research output: Contribution to journalArticle

Yasuda, M, Saeki, H, Nakashima, Y, Yukaya, T, Tsutsumi, S, Tajiri, H, Zaitsu, Y, Tsuda, Y, Kasagi, Y, Ando, K, Imamura, Y, Ohgaki, K, Akahoshi, T, Oki, E & Maehara, Y 2015, 'Treatment results of two-stage operation for the patients with esophageal cancer concomitant with liver dysfunction', Journal of Medical Investigation, vol. 62, no. 3, pp. 149-153. https://doi.org/10.2152/jmi.62.149
Yasuda, Mitsuhiro ; Saeki, Hiroshi ; Nakashima, Yuichiro ; Yukaya, Takafumi ; Tsutsumi, Satoshi ; Tajiri, Hirotada ; Zaitsu, Yoko ; Tsuda, Yasuo ; Kasagi, Yuta ; Ando, Koji ; Imamura, Yu ; Ohgaki, Kippei ; Akahoshi, Tomohiko ; Oki, Eiji ; Maehara, Yoshihiko. / Treatment results of two-stage operation for the patients with esophageal cancer concomitant with liver dysfunction. In: Journal of Medical Investigation. 2015 ; Vol. 62, No. 3. pp. 149-153.
@article{9a095a9b9f7d4c08afb5e1c56baf8047,
title = "Treatment results of two-stage operation for the patients with esophageal cancer concomitant with liver dysfunction",
abstract = "Purpose: The aim of this study was to clarify the usefulness of two-stage operation for the patients with esophageal cancer who have liver dysfunction. Methods: Eight patients with esophageal cancer concomitant with liver dysfunction who underwent two-stage operation were analyzed. The patients initially underwent an esophagectomy, a cervical esophagostomy and a tube jejunostomy, and reconstruction with gastric tube was performed after the recovery of patients' condition. Results: The average time of the 1st and 2nd stage operation was 410.0 min and 438.9 min, respectively. The average amount of blood loss in the 1st and 2nd stage operation was 433.5 ml and 1556.8 ml, respectively. The average duration between the operations was 29.8 days. The antesternal route was selected for 5 patients (62.5{\%}) and the retrosternal route was for 3 patients (37.5{\%}). In the 1st stage operation, no postoperative complications were observed, while, complications developed in 5 (62.5{\%}) patients, including 4 anastomotic leakages, after the 2nd stage operation. Pneumonia was not observed through two-stage operation. No in-hospital death was experienced. Conclusion: A two-stage operation might prevent the occurrence of critical postoperative complications for the patients with esophageal cancer concomitant with liver dysfunction.",
author = "Mitsuhiro Yasuda and Hiroshi Saeki and Yuichiro Nakashima and Takafumi Yukaya and Satoshi Tsutsumi and Hirotada Tajiri and Yoko Zaitsu and Yasuo Tsuda and Yuta Kasagi and Koji Ando and Yu Imamura and Kippei Ohgaki and Tomohiko Akahoshi and Eiji Oki and Yoshihiko Maehara",
year = "2015",
month = "9",
day = "18",
doi = "10.2152/jmi.62.149",
language = "English",
volume = "62",
pages = "149--153",
journal = "Journal of Medical Investigation",
issn = "1343-1420",
publisher = "University of Tokushima",
number = "3",

}

TY - JOUR

T1 - Treatment results of two-stage operation for the patients with esophageal cancer concomitant with liver dysfunction

AU - Yasuda, Mitsuhiro

AU - Saeki, Hiroshi

AU - Nakashima, Yuichiro

AU - Yukaya, Takafumi

AU - Tsutsumi, Satoshi

AU - Tajiri, Hirotada

AU - Zaitsu, Yoko

AU - Tsuda, Yasuo

AU - Kasagi, Yuta

AU - Ando, Koji

AU - Imamura, Yu

AU - Ohgaki, Kippei

AU - Akahoshi, Tomohiko

AU - Oki, Eiji

AU - Maehara, Yoshihiko

PY - 2015/9/18

Y1 - 2015/9/18

N2 - Purpose: The aim of this study was to clarify the usefulness of two-stage operation for the patients with esophageal cancer who have liver dysfunction. Methods: Eight patients with esophageal cancer concomitant with liver dysfunction who underwent two-stage operation were analyzed. The patients initially underwent an esophagectomy, a cervical esophagostomy and a tube jejunostomy, and reconstruction with gastric tube was performed after the recovery of patients' condition. Results: The average time of the 1st and 2nd stage operation was 410.0 min and 438.9 min, respectively. The average amount of blood loss in the 1st and 2nd stage operation was 433.5 ml and 1556.8 ml, respectively. The average duration between the operations was 29.8 days. The antesternal route was selected for 5 patients (62.5%) and the retrosternal route was for 3 patients (37.5%). In the 1st stage operation, no postoperative complications were observed, while, complications developed in 5 (62.5%) patients, including 4 anastomotic leakages, after the 2nd stage operation. Pneumonia was not observed through two-stage operation. No in-hospital death was experienced. Conclusion: A two-stage operation might prevent the occurrence of critical postoperative complications for the patients with esophageal cancer concomitant with liver dysfunction.

AB - Purpose: The aim of this study was to clarify the usefulness of two-stage operation for the patients with esophageal cancer who have liver dysfunction. Methods: Eight patients with esophageal cancer concomitant with liver dysfunction who underwent two-stage operation were analyzed. The patients initially underwent an esophagectomy, a cervical esophagostomy and a tube jejunostomy, and reconstruction with gastric tube was performed after the recovery of patients' condition. Results: The average time of the 1st and 2nd stage operation was 410.0 min and 438.9 min, respectively. The average amount of blood loss in the 1st and 2nd stage operation was 433.5 ml and 1556.8 ml, respectively. The average duration between the operations was 29.8 days. The antesternal route was selected for 5 patients (62.5%) and the retrosternal route was for 3 patients (37.5%). In the 1st stage operation, no postoperative complications were observed, while, complications developed in 5 (62.5%) patients, including 4 anastomotic leakages, after the 2nd stage operation. Pneumonia was not observed through two-stage operation. No in-hospital death was experienced. Conclusion: A two-stage operation might prevent the occurrence of critical postoperative complications for the patients with esophageal cancer concomitant with liver dysfunction.

UR - http://www.scopus.com/inward/record.url?scp=84942047843&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84942047843&partnerID=8YFLogxK

U2 - 10.2152/jmi.62.149

DO - 10.2152/jmi.62.149

M3 - Article

C2 - 26399339

AN - SCOPUS:84942047843

VL - 62

SP - 149

EP - 153

JO - Journal of Medical Investigation

JF - Journal of Medical Investigation

SN - 1343-1420

IS - 3

ER -