TY - JOUR
T1 - Trends in the practice of radiotherapy for localized prostate cancer in Japan
T2 - A preliminary patterns of care study report
AU - Nakamura, Katsumasa
AU - Ogawa, Kazuhiko
AU - Yamamoto, Tokihiro
AU - Sasaki, Tomonari
AU - Koizumi, Masahiko
AU - Teshima, Teruki
AU - Inoue, Toshihiko
N1 - Funding Information:
This study was supported by the Grant-in-Aid for Cancer Research (Nos 10–17 and 14–6) from the Ministry of Health, Labor and Welfare and a Grant from the Japan Society for the Promotion of Sciences. We thank all the radiation oncologists who participated in this study for their efforts in providing us with information that made these surveys possible.
PY - 2003/10/1
Y1 - 2003/10/1
N2 - Background: This is the first study to examine the characteristics and changes of the patterns of radiotherapy for prostate cancer in Japan. Methods: The Japanese Patterns of Care Study (PCS) conducted a random survey of 84 institutions nationwide. Detailed information was collected on prostate cancer patients without distant metastases, who received radiotherapy during 1996-1998 and 1999-2001. Results: The patients were divided into three groups: The Fresh Group (n = 338) was treated with radical radiotherapy with photon beams; the Surgery Group (n = 115) was treated after prostatectomy; and the Hormone-Refractory Group (n = 117) was treated after progression from hormonal therapy. In the Fresh Group, there was a decline in the fraction of patients with T3-4 tumors, from 65.2% in 1996-1998 to 43.9% in 1999-2001. In 1999-2001, a higher median dose of 69 Gy was irradiated as compared to 65 Gy in 1996-1998. In particular, the fraction of the patients treated with doses ≥70 Gy increased from 16.4% to 46.3%. In the Surgery Group, the percentage of clinical T3-4 tumors before prostatectomy decreased from 71.4% in 1996-1998 to 16.2% in 1999-2001. The median radiation dose of 60 Gy did not change, but the 1999-2001 results showed a decrease in the use of doses <60 Gy. In the Hormone-Refractory Group, the median dose increased from 60 Gy in 1996-1998 to 67 Gy in 1999-2001. Conclusion: These data suggest that radiation doses for prostate cancer in Japan have increased dramatically within a short period of time.
AB - Background: This is the first study to examine the characteristics and changes of the patterns of radiotherapy for prostate cancer in Japan. Methods: The Japanese Patterns of Care Study (PCS) conducted a random survey of 84 institutions nationwide. Detailed information was collected on prostate cancer patients without distant metastases, who received radiotherapy during 1996-1998 and 1999-2001. Results: The patients were divided into three groups: The Fresh Group (n = 338) was treated with radical radiotherapy with photon beams; the Surgery Group (n = 115) was treated after prostatectomy; and the Hormone-Refractory Group (n = 117) was treated after progression from hormonal therapy. In the Fresh Group, there was a decline in the fraction of patients with T3-4 tumors, from 65.2% in 1996-1998 to 43.9% in 1999-2001. In 1999-2001, a higher median dose of 69 Gy was irradiated as compared to 65 Gy in 1996-1998. In particular, the fraction of the patients treated with doses ≥70 Gy increased from 16.4% to 46.3%. In the Surgery Group, the percentage of clinical T3-4 tumors before prostatectomy decreased from 71.4% in 1996-1998 to 16.2% in 1999-2001. The median radiation dose of 60 Gy did not change, but the 1999-2001 results showed a decrease in the use of doses <60 Gy. In the Hormone-Refractory Group, the median dose increased from 60 Gy in 1996-1998 to 67 Gy in 1999-2001. Conclusion: These data suggest that radiation doses for prostate cancer in Japan have increased dramatically within a short period of time.
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U2 - 10.1093/jjco/hyg099
DO - 10.1093/jjco/hyg099
M3 - Article
C2 - 14623922
AN - SCOPUS:0642372936
VL - 33
SP - 527
EP - 532
JO - Japanese Journal of Clinical Oncology
JF - Japanese Journal of Clinical Oncology
SN - 0368-2811
IS - 10
ER -