Trends in the prevalence of myopia and myopic maculopathy in a Japanese population: The hisayama study

Emi Ueda, Miho Yasuda, Kohta Fujiwara, Sawako Hashimoto, Kyoko Ohno-Matsui, Jun Hata, Tatsuro Ishibashi, Toshiharu Ninomiya, Koh Hei Sonoda

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Abstract

PURPOSE. To examine trends in the prevalence of myopia and myopic maculopathy in a general Japanese population. METHODS. Residents of a Japanese community aged 40 years and older participated in surveys conducted in 2005, 2012, and 2017. Each participant underwent comprehensive eye examinations that included measurements of refractive error, axial lengths, and color fundus photography. Myopic maculopathy was defined according to the criteria of the Meta-analysis of Pathologic Myopia Study Group classification system. Trends in the prevalence of myopia and myopic maculopathy were tested by using a logistic regression analysis fitted by generalized estimating equations to account for individuals submitting to repeated examination. RESULTS. The age-adjusted frequencies of myopia increased significantly from 2005 to 2017 (myopia, 37.7%-45.8%; high myopia 5.8%-9.5%; all P for trend <0.001). The age-adjusted frequency of an axial length level of 26.5 mm or more increased significantly from 2005 to 2017 (3.6%-6.0%; P for trend <0.001). The age-adjusted prevalence of myopic maculopathy also increased significantly with time (1.6% in 2005, 3.0% in 2012 and 3.6% in 2017; P for trend <0.001). Upward trends were observed in the prevalence of diffuse chorioretinal atrophy and patchy chorioretinal atrophy (all P for trend <0.05). CONCLUSIONS. Our findings suggest that the prevalence of myopia and myopic maculopathy, especially diffuse chorioretinal atrophy and patchy chorioretinal atrophy, increased significantly over the past 12 years in a general Japanese population.

Original languageEnglish
Pages (from-to)2781-2786
Number of pages6
JournalInvestigative Ophthalmology and Visual Science
Volume60
Issue number8
DOIs
Publication statusPublished - Jul 2019

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Myopia
Atrophy
Population
Refractive Errors
Photography
Meta-Analysis
Color
Logistic Models
Regression Analysis

All Science Journal Classification (ASJC) codes

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

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Trends in the prevalence of myopia and myopic maculopathy in a Japanese population : The hisayama study. / Ueda, Emi; Yasuda, Miho; Fujiwara, Kohta; Hashimoto, Sawako; Ohno-Matsui, Kyoko; Hata, Jun; Ishibashi, Tatsuro; Ninomiya, Toshiharu; Sonoda, Koh Hei.

In: Investigative Ophthalmology and Visual Science, Vol. 60, No. 8, 07.2019, p. 2781-2786.

Research output: Contribution to journalArticle

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abstract = "PURPOSE. To examine trends in the prevalence of myopia and myopic maculopathy in a general Japanese population. METHODS. Residents of a Japanese community aged 40 years and older participated in surveys conducted in 2005, 2012, and 2017. Each participant underwent comprehensive eye examinations that included measurements of refractive error, axial lengths, and color fundus photography. Myopic maculopathy was defined according to the criteria of the Meta-analysis of Pathologic Myopia Study Group classification system. Trends in the prevalence of myopia and myopic maculopathy were tested by using a logistic regression analysis fitted by generalized estimating equations to account for individuals submitting to repeated examination. RESULTS. The age-adjusted frequencies of myopia increased significantly from 2005 to 2017 (myopia, 37.7{\%}-45.8{\%}; high myopia 5.8{\%}-9.5{\%}; all P for trend <0.001). The age-adjusted frequency of an axial length level of 26.5 mm or more increased significantly from 2005 to 2017 (3.6{\%}-6.0{\%}; P for trend <0.001). The age-adjusted prevalence of myopic maculopathy also increased significantly with time (1.6{\%} in 2005, 3.0{\%} in 2012 and 3.6{\%} in 2017; P for trend <0.001). Upward trends were observed in the prevalence of diffuse chorioretinal atrophy and patchy chorioretinal atrophy (all P for trend <0.05). CONCLUSIONS. Our findings suggest that the prevalence of myopia and myopic maculopathy, especially diffuse chorioretinal atrophy and patchy chorioretinal atrophy, increased significantly over the past 12 years in a general Japanese population.",
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T2 - The hisayama study

AU - Ueda, Emi

AU - Yasuda, Miho

AU - Fujiwara, Kohta

AU - Hashimoto, Sawako

AU - Ohno-Matsui, Kyoko

AU - Hata, Jun

AU - Ishibashi, Tatsuro

AU - Ninomiya, Toshiharu

AU - Sonoda, Koh Hei

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N2 - PURPOSE. To examine trends in the prevalence of myopia and myopic maculopathy in a general Japanese population. METHODS. Residents of a Japanese community aged 40 years and older participated in surveys conducted in 2005, 2012, and 2017. Each participant underwent comprehensive eye examinations that included measurements of refractive error, axial lengths, and color fundus photography. Myopic maculopathy was defined according to the criteria of the Meta-analysis of Pathologic Myopia Study Group classification system. Trends in the prevalence of myopia and myopic maculopathy were tested by using a logistic regression analysis fitted by generalized estimating equations to account for individuals submitting to repeated examination. RESULTS. The age-adjusted frequencies of myopia increased significantly from 2005 to 2017 (myopia, 37.7%-45.8%; high myopia 5.8%-9.5%; all P for trend <0.001). The age-adjusted frequency of an axial length level of 26.5 mm or more increased significantly from 2005 to 2017 (3.6%-6.0%; P for trend <0.001). The age-adjusted prevalence of myopic maculopathy also increased significantly with time (1.6% in 2005, 3.0% in 2012 and 3.6% in 2017; P for trend <0.001). Upward trends were observed in the prevalence of diffuse chorioretinal atrophy and patchy chorioretinal atrophy (all P for trend <0.05). CONCLUSIONS. Our findings suggest that the prevalence of myopia and myopic maculopathy, especially diffuse chorioretinal atrophy and patchy chorioretinal atrophy, increased significantly over the past 12 years in a general Japanese population.

AB - PURPOSE. To examine trends in the prevalence of myopia and myopic maculopathy in a general Japanese population. METHODS. Residents of a Japanese community aged 40 years and older participated in surveys conducted in 2005, 2012, and 2017. Each participant underwent comprehensive eye examinations that included measurements of refractive error, axial lengths, and color fundus photography. Myopic maculopathy was defined according to the criteria of the Meta-analysis of Pathologic Myopia Study Group classification system. Trends in the prevalence of myopia and myopic maculopathy were tested by using a logistic regression analysis fitted by generalized estimating equations to account for individuals submitting to repeated examination. RESULTS. The age-adjusted frequencies of myopia increased significantly from 2005 to 2017 (myopia, 37.7%-45.8%; high myopia 5.8%-9.5%; all P for trend <0.001). The age-adjusted frequency of an axial length level of 26.5 mm or more increased significantly from 2005 to 2017 (3.6%-6.0%; P for trend <0.001). The age-adjusted prevalence of myopic maculopathy also increased significantly with time (1.6% in 2005, 3.0% in 2012 and 3.6% in 2017; P for trend <0.001). Upward trends were observed in the prevalence of diffuse chorioretinal atrophy and patchy chorioretinal atrophy (all P for trend <0.05). CONCLUSIONS. Our findings suggest that the prevalence of myopia and myopic maculopathy, especially diffuse chorioretinal atrophy and patchy chorioretinal atrophy, increased significantly over the past 12 years in a general Japanese population.

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