TY - JOUR
T1 - Trends in the prevalence of myopia and myopic maculopathy in a Japanese population
T2 - The hisayama study
AU - Ueda, Emi
AU - Yasuda, Miho
AU - Fujiwara, Kohta
AU - Hashimoto, Sawako
AU - Ohno-Matsui, Kyoko
AU - Hata, Jun
AU - Ishibashi, Tatsuro
AU - Ninomiya, Toshiharu
AU - Sonoda, Koh Hei
N1 - Funding Information:
The authors thank the residents of the town of Hisayama for their participation in the survey and the staff of the Division of Health and Welfare of Hisayama for their cooperation with this study. The statistical analyses were carried out using the computer resource offered under the category of General Projects by Research Institute for Information Technology, Kyushu University. Supported by Grants-in-Aid for Scientific Research (Tokyo, Japan) (A; JP16H02644 and JP16H02692), (B; JP16H05850, JP16H05557, JP17H04126, and JP18H02737) and (C; JP16K09244, JP17K09114, JP17K09113, JP17K01853, JP18K07565, and JP18K09412) and Grants-in-Aid for Early-Career Scientists (Tokyo, Japan) (JP18K17925, JP18K17382, and JP18K16960) from the Ministry of Education, Culture, Sports, Science and Technology of Japan; by Health and Labour Sciences Research Grants of the Ministry of Health, Labour and Welfare of Japan (Tokyo, Japan) (H29- Junkankitou-Ippan-003 and H30-Shokuhin-[Sitei]-005); and by Grants-in-Aid from the Japan Agency for Medical Research and Development (Tokyo, Japan) (JP18dk0207025, JP18ek0210082, JP18gm0610007, JP18ek0210083, JP18km0405202, JP18ek0210080, and JP18fk0108075).
Funding Information:
Supported by Grants-in-Aid for Scientific Research (Tokyo, Japan) (A; JP16H02644 and JP16H02692), (B; JP16H05850, JP16H05557, JP17H04126, and JP18H02737) and (C; JP16K09244, JP17K09114, JP17K09113, JP17K01853, JP18K07565, and JP18K09412) and Grants-in-Aid for Early-Career Scientists (Tokyo, Japan) (JP18K17925, JP18K17382, and JP18K16960) from the Ministry of Education, Culture, Sports, Science and Technology of Japan; by Health and Labour Sciences Research Grants of the Ministry of Health, Labour and Welfare of Japan (Tokyo, Japan) (H29-Junkankitou-Ippan-003 and H30-Shokuhin-[Sitei]-005); and by Grants-in-Aid from the Japan Agency for Medical Research and Development (Tokyo, Japan) (JP18dk0207025, JP18ek0210082, JP18gm0610007, JP18ek0210083, JP18km0405202, JP18ek0210080, and JP18fk0108075).
Publisher Copyright:
© 2019 The Authors.
Copyright:
Copyright 2019 Elsevier B.V., All rights reserved.
PY - 2019/7
Y1 - 2019/7
N2 - PURPOSE. To examine trends in the prevalence of myopia and myopic maculopathy in a general Japanese population. METHODS. Residents of a Japanese community aged 40 years and older participated in surveys conducted in 2005, 2012, and 2017. Each participant underwent comprehensive eye examinations that included measurements of refractive error, axial lengths, and color fundus photography. Myopic maculopathy was defined according to the criteria of the Meta-analysis of Pathologic Myopia Study Group classification system. Trends in the prevalence of myopia and myopic maculopathy were tested by using a logistic regression analysis fitted by generalized estimating equations to account for individuals submitting to repeated examination. RESULTS. The age-adjusted frequencies of myopia increased significantly from 2005 to 2017 (myopia, 37.7%-45.8%; high myopia 5.8%-9.5%; all P for trend <0.001). The age-adjusted frequency of an axial length level of 26.5 mm or more increased significantly from 2005 to 2017 (3.6%-6.0%; P for trend <0.001). The age-adjusted prevalence of myopic maculopathy also increased significantly with time (1.6% in 2005, 3.0% in 2012 and 3.6% in 2017; P for trend <0.001). Upward trends were observed in the prevalence of diffuse chorioretinal atrophy and patchy chorioretinal atrophy (all P for trend <0.05). CONCLUSIONS. Our findings suggest that the prevalence of myopia and myopic maculopathy, especially diffuse chorioretinal atrophy and patchy chorioretinal atrophy, increased significantly over the past 12 years in a general Japanese population.
AB - PURPOSE. To examine trends in the prevalence of myopia and myopic maculopathy in a general Japanese population. METHODS. Residents of a Japanese community aged 40 years and older participated in surveys conducted in 2005, 2012, and 2017. Each participant underwent comprehensive eye examinations that included measurements of refractive error, axial lengths, and color fundus photography. Myopic maculopathy was defined according to the criteria of the Meta-analysis of Pathologic Myopia Study Group classification system. Trends in the prevalence of myopia and myopic maculopathy were tested by using a logistic regression analysis fitted by generalized estimating equations to account for individuals submitting to repeated examination. RESULTS. The age-adjusted frequencies of myopia increased significantly from 2005 to 2017 (myopia, 37.7%-45.8%; high myopia 5.8%-9.5%; all P for trend <0.001). The age-adjusted frequency of an axial length level of 26.5 mm or more increased significantly from 2005 to 2017 (3.6%-6.0%; P for trend <0.001). The age-adjusted prevalence of myopic maculopathy also increased significantly with time (1.6% in 2005, 3.0% in 2012 and 3.6% in 2017; P for trend <0.001). Upward trends were observed in the prevalence of diffuse chorioretinal atrophy and patchy chorioretinal atrophy (all P for trend <0.05). CONCLUSIONS. Our findings suggest that the prevalence of myopia and myopic maculopathy, especially diffuse chorioretinal atrophy and patchy chorioretinal atrophy, increased significantly over the past 12 years in a general Japanese population.
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U2 - 10.1167/iovs.19-26580
DO - 10.1167/iovs.19-26580
M3 - Article
C2 - 31260519
AN - SCOPUS:85069261434
VL - 60
SP - 2781
EP - 2786
JO - Investigative Ophthalmology
JF - Investigative Ophthalmology
SN - 0146-0404
IS - 8
ER -